Department of Internal Medicine, Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan, Malaysia.
Int J Rheum Dis. 2012 Oct;15(5):468-77. doi: 10.1111/j.1756-185X.2012.01753.x. Epub 2012 Jun 29.
To determine the prevalence of sexual dysfunction (FSD) among women with rheumatoid arthritis attending the Rheumatology Clinic in Universiti Kebangsaan Malaysia Medical Centre (UKMMC) and Hospital Putrajaya, Malaysia, and to determine its associations with potential clinical and disease activity factors.
This was a cross-sectional study involving women with rheumatoid arthritis between the ages of 20 and 60 years. A validated Malay Version Female Sexual Function Index (MVFSFI) was administered to diagnose FSD. Sociodemographic and disease activity profiles were obtained and those who had and did not have FSD were compared.
Among 63 respondents, 51 patients were included in the analysis for FSD. The prevalence of FSD in women with rheumatoid arthritis attending UKMMC and Hospital Putrajaya Rheumatology Clinic was 29.4%. Erythrocyte sedimentation rate (ESR) and Disease Activity Score in 28 joints (DAS28-ESR) correlates with MVFSFI score with r=-0.364 (P=0.009) and r=-0.268 (P=0.057), respectively. Sociodemographic factors that correlate with MVFSFI score were: patient's age (r=0.520, P<0.001); duration of marriage (r=-0.355, P=0.001); husband's age (r=-0.460, P=0.001); age of oldest child (r=-0.449, P=0.001); and age of youngest child (r=-0.627, P<0.001).
We found in this study that the prevalence of FSD in rheumatoid arthritis in our centers was 29.4%. Age and family dynamics appear to be more important predictors compared to disease activity.
确定在马来西亚国立大学医学中心(UKMMC)和布城医院风湿科就诊的类风湿关节炎女性患者性功能障碍(FSD)的患病率,并确定其与潜在临床和疾病活动因素的相关性。
这是一项横断面研究,纳入年龄在 20 至 60 岁之间的类风湿关节炎女性患者。采用经过验证的马来语版女性性功能指数(MVFSFI)进行诊断 FSD。获得社会人口统计学和疾病活动概况,并对有和没有 FSD 的患者进行比较。
在 63 名受访者中,有 51 名患者纳入 FSD 分析。在 UKMMC 和布城医院风湿科就诊的类风湿关节炎女性患者中,FSD 的患病率为 29.4%。红细胞沉降率(ESR)和 28 关节疾病活动评分(DAS28-ESR)与 MVFSFI 评分相关,r 值分别为-0.364(P=0.009)和-0.268(P=0.057)。与 MVFSFI 评分相关的社会人口统计学因素包括:患者年龄(r=0.520,P<0.001);婚姻持续时间(r=-0.355,P=0.001);丈夫年龄(r=-0.460,P=0.001);最大孩子年龄(r=-0.449,P=0.001);最小孩子年龄(r=-0.627,P<0.001)。
我们在这项研究中发现,我们中心类风湿关节炎患者的 FSD 患病率为 29.4%。年龄和家庭动态似乎比疾病活动更重要的预测因素。