Cell-based interventions for therapeutic angiogenesis: review of potential cell sources.
作者信息
Brenes Robert A, Bear Mackenzie, Jadlowiec Caroline, Goodwin Matthew, Hashim Peter, Protack Clinton D, Ziegler Kenneth R, Li Xin, Model Lynn S, Lv Wei, Collins Michael J, Dardik Alan
机构信息
Interdepartmental Program in Vascular Biology and Therapeutics, Yale University School of Medicine, New Haven, CT 06520-8089, USA.
出版信息
Vascular. 2012 Dec;20(6):360-8. doi: 10.1258/vasc.2011.201205. Epub 2012 Oct 19.
Alternative therapies are currently being developed to treat patients with chronic limb ischemia who are unable to be revascularized in order to avoid amputation. Cell-based therapy using mononuclear cells is gaining attention as many clinical trials are currently underway. We review cell differentiation along with the different potential cell sources for use in therapeutic angiogenesis.