• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

论“修复瘫痪性脊髓损伤后的自主运动控制”。

Comment on "Restoring voluntary control of locomotion after paralyzing spinal cord injury".

机构信息

Nencki Institute of Experimental Biology, Department of Neurophysiology, Warsaw, Poland.

出版信息

Science. 2012 Oct 19;338(6105):328; author reply 328. doi: 10.1126/science.1226274.

DOI:10.1126/science.1226274
PMID:23087231
Abstract

Van den Brand et al. (Reports, 1 June 2012, p. 1182) claim to have restored voluntary control of locomotion after paralyzing spinal cord injury. They have not considered recent findings that their upright posture paradigm contributes to locomotor capability after such injuries. We propose that postural adjustments that activate the locomotor central pattern generator in the upright posture, rather than direct voluntary control of locomotion, account for their results.

摘要

范登布兰德等人(2012 年 6 月 1 日,第 1182 页)声称,他们已经在脊髓损伤后恢复了对运动的自主控制。然而,他们没有考虑到最近的研究发现,他们的直立姿势范式有助于此类损伤后的运动能力。我们提出,在直立姿势中激活运动中枢模式发生器的姿势调整,而不是直接的运动自主控制,解释了他们的结果。

相似文献

1
Comment on "Restoring voluntary control of locomotion after paralyzing spinal cord injury".论“修复瘫痪性脊髓损伤后的自主运动控制”。
Science. 2012 Oct 19;338(6105):328; author reply 328. doi: 10.1126/science.1226274.
2
Restoring voluntary control of locomotion after paralyzing spinal cord injury.恢复瘫痪性脊髓损伤后的自主运动控制。
Science. 2012 Jun 1;336(6085):1182-5. doi: 10.1126/science.1217416.
3
Cortical motor areas and their properties: implications for neuroprosthetics.皮质运动区及其特性:对神经假体的启示
Prog Brain Res. 2000;128:135-60. doi: 10.1016/s0079-6123(00)28013-8.
4
Cortex-dependent recovery of unassisted hindlimb locomotion after complete spinal cord injury in adult rats.成年大鼠完全性脊髓损伤后皮质依赖性非辅助后肢运动功能的恢复
Elife. 2017 Jun 29;6:e23532. doi: 10.7554/eLife.23532.
5
The upright posture improves plantar stepping and alters responses to serotonergic drugs in spinal rats.直立姿势改善了脊髓损伤大鼠的足底踏步行走,并改变了对 5-羟色胺能药物的反应。
J Physiol. 2012 Apr 1;590(7):1721-36. doi: 10.1113/jphysiol.2011.224931. Epub 2012 Feb 20.
6
Engagement of the Rat Hindlimb Motor Cortex across Natural Locomotor Behaviors.大鼠后肢运动皮层在自然运动行为中的参与情况。
J Neurosci. 2016 Oct 5;36(40):10440-10455. doi: 10.1523/JNEUROSCI.4343-15.2016.
7
Ipsilesional Motor Cortex Plasticity Participates in Spontaneous Hindlimb Recovery after Lateral Hemisection of the Thoracic Spinal Cord in the Rat.损伤侧运动皮层的可塑性参与了大鼠胸段脊髓横断后自发性后肢恢复。
J Neurosci. 2018 Nov 14;38(46):9977-9988. doi: 10.1523/JNEUROSCI.1062-18.2018. Epub 2018 Oct 9.
8
Combined motor cortex and spinal cord neuromodulation promotes corticospinal system functional and structural plasticity and motor function after injury.联合运动皮层和脊髓神经调节促进损伤后皮质脊髓系统的功能和结构可塑性以及运动功能。
Exp Neurol. 2016 Mar;277:46-57. doi: 10.1016/j.expneurol.2015.12.008. Epub 2015 Dec 18.
9
Motor cortex and spinal cord neuromodulation promote corticospinal tract axonal outgrowth and motor recovery after cervical contusion spinal cord injury.运动皮层和脊髓神经调节促进颈髓挫伤性脊髓损伤后皮质脊髓束轴突生长和运动恢复。
Exp Neurol. 2017 Nov;297:179-189. doi: 10.1016/j.expneurol.2017.08.004. Epub 2017 Aug 10.
10
Rapid recovery and altered neurochemical dependence of locomotor central pattern generation following lumbar neonatal spinal cord injury.腰新生儿脊髓损伤后运动中枢模式发生器的快速恢复和神经化学依赖改变。
J Physiol. 2018 Jan 15;596(2):281-303. doi: 10.1113/JP274484. Epub 2017 Dec 3.

引用本文的文献

1
Cerebral Theta-Burst Stimulation Combined with Physiotherapy in Patients with Incomplete Spinal Cord Injury: A Pilot Randomized Controlled Trial.经颅磁刺激联合物理疗法治疗不完全性脊髓损伤患者的前瞻性随机对照研究
J Rehabil Med. 2023 Feb 13;55:jrm00375. doi: 10.2340/jrm.v55.4375.
2
Motor improvements enabled by spinal cord stimulation combined with physical training after spinal cord injury: review of experimental evidence in animals and humans.脊髓损伤后脊髓刺激联合体育训练实现的运动功能改善:动物和人类实验证据综述
Bioelectron Med. 2021 Oct 28;7(1):16. doi: 10.1186/s42234-021-00077-5.
3
Formation of a novel supraspinal-spinal connectome that relearns the same motor task after complete paralysis.
形成一种新的脊髓上-脊髓连接组,在完全瘫痪后重新学习相同的运动任务。
J Neurophysiol. 2021 Sep 1;126(3):957-966. doi: 10.1152/jn.00422.2020. Epub 2021 Aug 18.
4
A fair and EMG-validated comparison of recruitment criteria, musculotendon models and muscle coordination strategies, for the inverse-dynamics based optimization of muscle forces during gait.对步态中基于逆动力学的肌肉力优化的募集准则、肌肉肌腱模型和肌肉协调策略进行公平且肌电图验证的比较。
J Neuroeng Rehabil. 2021 Jan 28;18(1):17. doi: 10.1186/s12984-021-00806-6.
5
Cortico-reticulo-spinal circuit reorganization enables functional recovery after severe spinal cord contusion.皮质-网状脊髓环路重建使严重脊髓挫伤后功能恢复成为可能。
Nat Neurosci. 2018 Apr;21(4):576-588. doi: 10.1038/s41593-018-0093-5. Epub 2018 Mar 19.
6
A brainstem bypass for spinal cord injury.一种用于脊髓损伤的脑干搭桥术。
Nat Neurosci. 2018 Apr;21(4):457-458. doi: 10.1038/s41593-018-0099-z.
7
5-HT₂ and 5-HT₇ receptor agonists facilitate plantar stepping in chronic spinal rats through actions on different populations of spinal neurons.5-羟色胺₂和5-羟色胺₇受体激动剂通过作用于不同的脊髓神经元群体,促进慢性脊髓大鼠的足底踏步。
Front Neural Circuits. 2014 Aug 19;8:95. doi: 10.3389/fncir.2014.00095. eCollection 2014.
8
Preclinical evidence supporting the clinical development of central pattern generator-modulating therapies for chronic spinal cord-injured patients.支持针对慢性脊髓损伤患者的中枢模式发生器调节疗法进行临床开发的临床前证据。
Front Hum Neurosci. 2014 May 30;8:272. doi: 10.3389/fnhum.2014.00272. eCollection 2014.
9
Therapeutic intraspinal stimulation to generate activity and promote long-term recovery.经治疗性脊髓内刺激产生的活动并促进长期恢复。
Front Neurosci. 2014 Feb 27;8:21. doi: 10.3389/fnins.2014.00021. eCollection 2014.
10
Central pattern generator for locomotion: anatomical, physiological, and pathophysiological considerations.运动的中枢模式发生器:解剖学、生理学和病理生理学的考虑。
Front Neurol. 2013 Feb 8;3:183. doi: 10.3389/fneur.2012.00183. eCollection 2012.