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口腔黏膜原发性黑色素瘤:一例报告并文献复习

Primary melanoma of oral mucosa: A case report and review of literature.

作者信息

Bhullar Raman Preet Kaur, Bhullar Amandeep, Vanaki Srinivas S, Puranik R S, Sudhakara M, Kamat Mamata S

机构信息

Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India.

出版信息

Dent Res J (Isfahan). 2012 May;9(3):353-6.

PMID:23087745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3469906/
Abstract

Primary oral melanoma is a rare neoplasm of melanocytic origin, accounting for 0.5% of all oral malignancies. The "chameleonic" presentation of a mainly asymptomatic condition, rarity of this lesion, poor prognosis, and the necessity of a highly specialized treatment are factors that should be seriously considered by the involved health provider. Here is a case report presenting a malignant melanoma of oral mucosa in 48-year-old male patient on maxillary gingiva. The lesion was removed by partial maxillectomy and patient is disease free after 11 months of regular followup. This case provides an example of how dental clinicians play a major role in the identification of pigmented lesions of oral cavity and also emphasize on the fact that any pigmented lesion detected in the oral cavity may exhibit potential growth and should be submitted to biopsy to exclude malignancy.

摘要

原发性口腔黑色素瘤是一种罕见的黑素细胞起源的肿瘤,占所有口腔恶性肿瘤的0.5%。这种主要无症状的“变色龙”表现、该病变的罕见性、预后不良以及高度专业化治疗的必要性,都是相关医疗服务提供者应认真考虑的因素。本文报告一例48岁男性患者上颌牙龈的口腔黏膜恶性黑色素瘤病例。该病变通过部分上颌骨切除术切除,经过11个月的定期随访,患者无疾病复发。该病例展示了牙科临床医生在口腔色素沉着病变识别中如何发挥主要作用,同时也强调了在口腔中检测到的任何色素沉着病变都可能有潜在生长,应进行活检以排除恶性肿瘤这一事实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b1a/3469906/79ac91059fa7/DRJ-9-353-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b1a/3469906/3c490e92af22/DRJ-9-353-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b1a/3469906/c9c5d02d749f/DRJ-9-353-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b1a/3469906/79ac91059fa7/DRJ-9-353-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b1a/3469906/3c490e92af22/DRJ-9-353-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b1a/3469906/c9c5d02d749f/DRJ-9-353-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b1a/3469906/79ac91059fa7/DRJ-9-353-g003.jpg

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