Bloch B, Lenys D, Gouget A, Fellmann D, Bugnon C
C R Seances Soc Biol Fil. 1979;173(4):719-24.
In rat hypothalamus intraventricularly injected with colchicine, the same neurons of the ventral region are stained with I.S. against alpha and beta-endorphin, (1-24) and (17-39) ACTH, alpha and beta-MSH, and beta-LPH. They are distinct from those producing LH-RH, somatostatin, neurophysin, and dopamine. These results suggest that the same neurons elaborate peptides identical with or immunologically related to endorphins, ACTH, alpha-MSH and beta-LPH, probably issued from a common precursor.
在向大鼠下丘脑脑室内注射秋水仙碱后，腹侧区的相同神经元被免疫细胞化学法染色，可检测到α和β - 内啡肽、（1 - 24）和（17 - 39）促肾上腺皮质激素、α和β - 促黑素以及β - 促脂素。它们与产生促黄体生成素释放激素、生长抑素、神经垂体素和多巴胺的神经元不同。这些结果表明，相同的神经元能合成与内啡肽、促肾上腺皮质激素、α - 促黑素和β - 促脂素相同或免疫相关的肽类，这些肽类可能来自一个共同的前体。
