在中性 pH 条件下一锅法制备具有高荧光性能的碲化镉/硫化镉量子点用于生物应用。

One-pot preparation of highly fluorescent cadmium telluride/cadmium sulfide quantum dots under neutral-pH condition for biological applications.

机构信息

ARC Centre of Excellence for Functional Nanomaterials, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Queensland 4072, Australia.

出版信息

J Colloid Interface Sci. 2013 Jan 15;390(1):3-10. doi: 10.1016/j.jcis.2012.08.003. Epub 2012 Oct 2.

DOI:10.1016/j.jcis.2012.08.003

PMID:23089593

Abstract

Water-soluble CdTe/CdS quantum dots (QDs) with tuneable emissions were prepared in aqueous solution at pH=6-7 via refluxing and hydrothermal treatment. The resultant CdTe/CdS QDs are stabilized with mercaptosuccinic acid (MSA) and show high fluorescence quantum yields (maximum QY is 84%). Characterization with UV-Vis, PL, XPS, XRD and TEM demonstrates a core (CdTe)-shell (CdS) structure, which leads to high fluorescence quantum yields. The effective protection from CdS shell and MSA enables CdTe QDs to be chemically stable in a pH range of 6-9 and less toxic. These merits make our CdTe/CdS QDs very promising for bio-imaging applications, as exemplified by labelling HEK 293 cells.

摘要

在 pH=6-7 的水溶液中，通过回流和水热法制备了具有可调发射的水溶性 CdTe/CdS 量子点（QDs）。所得的 CdTe/CdS QDs 用巯基丁二酸（MSA）稳定，具有高荧光量子产率（最大 QY 为 84%）。通过紫外-可见、PL、XPS、XRD 和 TEM 的表征，证明了核（CdTe）-壳（CdS）结构，这导致了高荧光量子产率。CdS 壳和 MSA 的有效保护使 CdTe QDs 在 pH 值为 6-9 的范围内具有化学稳定性和低毒性。这些优点使我们的 CdTe/CdS QDs 非常有前途的用于生物成像应用，例如标记 HEK 293 细胞。