University of Colorado, Denver, Aurora, CO 80247, USA.
Spine (Phila Pa 1976). 2013 Jan 1;38(1):E38-42. doi: 10.1097/BRS.0b013e3182793e51.
This is a case report.
To report a case of soft-tissue reaction to wear debris and osteolysis around a pedicle screw after posterior spine fusion in a pediatric patient.
Posterior spine fusion with instrumentation is a standard procedure for stabilization and curve correction in patients with scoliosis. Late operative site pain accounts for the highest frequency of reoperation. Debris accumulation for steel and titanium constructs occurs at the pedicle screw-rod junction. Cellular reaction to metal wear may be responsible for osteolysis and aseptic loosening around spinal implants.
A 14-year-old male patient with neurofibromatosis and right thoracic scoliosis of 50° underwent posterior spine fusion from T2 to T10. The postoperative course was complicated by continuous pain, and imaging studies demonstrated hardware failure, requiring a revision and subsequent development of a perihilar opacity of unknown origin. Further studies demonstrated hypermobility with adjacent soft-tissue reactivity and inflammation surrounding the right T5 transpedicle screw.
After hardware removal, the patient's recovery was uneventful. Six months later, a repeated computed tomographic scan demonstrated resolution of the previously described soft-tissue mass and a satisfactory fusion of the thoracic spine.
Metal wear debris can form in pediatric patients during the healing process after spinal fusions or when pseudarthrosis is present. Clinically, this manifests as back pain with a possible aseptic inflammatory abscess. Hardware removal can achieve resolution of symptoms and regression of inflammation.
本研究为病例报告。
报告一例儿童脊柱融合术后椎弓根螺钉周围磨损颗粒引起的软组织反应和骨溶解。
脊柱后路融合内固定术是脊柱侧凸患者稳定和矫正脊柱畸形的标准方法。晚期手术部位疼痛是再次手术的最高频率原因。钢钛结构的颗粒堆积发生在椎弓根螺钉-棒交界处。金属磨损的细胞反应可能导致脊柱植入物周围的骨溶解和无菌性松动。
一名 14 岁男性,患有神经纤维瘤病和右胸 50°脊柱侧凸,行 T2-T10 后路脊柱融合术。术后过程中出现持续疼痛,影像学检查显示内固定失败,需要进行翻修,随后出现了一个来源不明的肺门周围不透明影。进一步的研究显示,右侧 T5 经椎弓根螺钉周围的软组织有过度活动和炎症反应。
去除内固定物后,患者恢复顺利。6 个月后,重复 CT 扫描显示先前描述的软组织肿块已消失,胸椎融合良好。
在脊柱融合术后愈合过程中或假关节存在时,儿童患者体内可能会形成金属磨损颗粒。临床上,这表现为背痛,并可能伴有无菌性炎症脓肿。去除内固定物可缓解症状和炎症消退。