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美沙酮维持治疗期间的性功能障碍及其对患者生活和治疗的影响:中国南方的一项定性研究。

Sexual dysfunction during methadone maintenance treatment and its influence on patient's life and treatment: a qualitative study in South China.

机构信息

Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, China.

出版信息

Psychol Health Med. 2013;18(3):321-9. doi: 10.1080/13548506.2012.729845. Epub 2012 Oct 24.

Abstract

Methadone maintenance treatment (MMT) has become an important modality of substitution treatment for opioid addicts in China since 2006. However, data are limited regarding the change in sexual function from heroin use to MMT and the influence of sexual dysfunction (SD) during MMT on patient's life and treatment. Face-to-face in-depth interviews were conducted with 13 male and 14 female MMT patients, five of their partners, and three clinicians. The interviews took place in four MMT clinics in Guangdong Province between August 2010 and February 2011. The patients and their partners were asked separately for their perceptions of patient's sexual function during MMT, and the influence of SD on personal/family life and treatment. The main SD problems patients perceived were libido inhibition and decreased sexual pleasure. Methadone was thought to have a stronger inhibition effect on sexual desire than heroin. SD decreased quality of patient's sexual life and damaged intimate relationships. There was a gender difference in coping with SD. Men generally tended to refuse, escape, or alienate their partners. Women tended to hide sexual listlessness, endure sexual activity and tried to satisfy their partners. SD might increase risk of voluntary dropout from treatment and illicit drug use during treatment. Patients with SD did not get any effective therapy from clinicians and they also lacked skills on coping with SD-related problems. Sexual dysfunction prevented patients from reconstructing a normal intimate relationship, and affected stability of maintenance treatment. Response to patient's SD and SD-related problems from clinicians was inadequate. There is a need to develop a clinical guide to deal with both SD itself and SD-related problems.

摘要

美沙酮维持治疗(MMT)自 2006 年以来已成为中国阿片类药物滥用者替代治疗的重要模式。然而,关于从海洛因使用到 MMT 的性功能变化以及 MMT 期间性功能障碍(SD)对患者生活和治疗的影响的数据有限。2010 年 8 月至 2011 年 2 月,在广东省的四个 MMT 诊所对 13 名男性和 14 名女性 MMT 患者、他们的五名伴侣和三名临床医生进行了面对面的深入访谈。访谈分别询问了患者及其伴侣对患者在 MMT 期间性功能的看法,以及 SD 对个人/家庭生活和治疗的影响。患者感知到的主要 SD 问题是性欲抑制和性快感降低。美沙酮被认为对性欲的抑制作用比海洛因更强。SD 降低了患者性生活的质量,破坏了亲密关系。应对 SD 的方式存在性别差异。男性通常倾向于拒绝、逃避或疏远伴侣。女性倾向于隐瞒性冷漠,忍受性行为并试图满足伴侣。SD 可能会增加自愿退出治疗和治疗期间非法药物使用的风险。有 SD 的患者没有从临床医生那里得到任何有效的治疗,他们也缺乏应对 SD 相关问题的技能。SD 阻止了患者重建正常的亲密关系,并影响了维持治疗的稳定性。临床医生对患者的 SD 和 SD 相关问题的反应不足。需要制定一个临床指南来处理 SD 本身和 SD 相关问题。

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