Zhong Bao-Liang, Xu Yan-Min, Zhu Jun-Hong, Li Hong-Jie
Research Center for Psychological and Health Sciences, China University of Geosciences, Wuhan, Hubei Province, China.
Affiliated Wuhan Mental Health Center, Tongji Medical College of Huazhong University of Science & Technology, Wuhan, Hubei Province, China,
J Pain Res. 2018 Sep 10;11:1789-1794. doi: 10.2147/JPR.S177564. eCollection 2018.
Pain is potentially associated with sexual dysfunction. Both sexual dysfunction and pain are common in methadone-maintained patients, but the association of pain with sexual dysfunction in methadone-maintained patients is rarely studied. This study examined the association between pain and sexual life satisfaction (SLS) in Chinese patients receiving methadone maintenance treatment (MMT).
A total of 477 methadone-maintained patients who recently had sex with their sex partners were recruited from three MMT clinics in Wuhan, China. SLS was assessed with a single question, and the sociodemographic, psychological, and clinical data were collected with standardized questionnaires. Pain intensity was assessed with the 5-point verbal rating scale. Multiple ordinary logistic regression was used to control for potential confounders that may bias the pain-SLS relationship.
The prevalence of self-reported dissatisfaction with one's sexual life was significantly higher in patients with clinically significant pain (CSP) than those without CSP (41.5% vs 19.4%, χ =23.567, <0.001). After controlling for potential sociodemographic, psychological, and clinical confounders, CSP was still significantly and independently associated with an increase in sexual life dissatisfaction (OR =1.89, =0.011).
Pain is significantly associated with low SLS in methadone-maintained patients. Appropriate pain management might improve SLS of patients receiving MMT.
疼痛可能与性功能障碍相关。性功能障碍和疼痛在美沙酮维持治疗的患者中都很常见，但美沙酮维持治疗患者中疼痛与性功能障碍的关联很少被研究。本研究调查了接受美沙酮维持治疗（MMT）的中国患者中疼痛与性生活满意度（SLS）之间的关联。
从中国武汉的三家MMT诊所招募了477名近期与性伴侣有过性行为的美沙酮维持治疗患者。通过一个问题评估SLS，并用标准化问卷收集社会人口学、心理和临床数据。用5分言语评定量表评估疼痛强度。采用多重普通逻辑回归来控制可能使疼痛与SLS关系产生偏差的潜在混杂因素。
有临床显著疼痛（CSP）的患者自我报告对性生活不满意的患病率显著高于无CSP的患者（41.5%对19.4%，χ =23.567，<0.001）。在控制了潜在的社会人口学、心理和临床混杂因素后，CSP仍与性生活不满意的增加显著且独立相关（OR =1.89，=0.011）。
在美沙酮维持治疗患者中，疼痛与低SLS显著相关。适当的疼痛管理可能会改善接受MMT患者的SLS。
