Cassidy Darby, Jarvi Keith, Grober Ethan, Lo Kirk
University Hospital of Northern British Columbia, Prince George, BC;
Can Urol Assoc J. 2012 Aug;6(4):266-8. doi: 10.5489/cuaj.11064.
: Varicocele remains the most commonly identified correctable cause of male factor infertility. Surgical correction is the most commonly performed technique to treat varicoceles with a technical failure rate of less than 5%. An attractive alternative to surgery is the selective catheterization and embolization of the gonadal vein. This data are limited by small series.
: We reviewed a total of 158 patients. These patients underwent embolization for clinical varicoceles and male factor infertility between 2004 and 2008. Of these, 56% underwent attempted bilateral embolization, 43% unilateral left-sided embolization and 1.3% unilateral right-sided embolization.
: Of these patients who underwent attempted bilateral embolization, 19.3% did not experience a successful obliteration of the right gonadal vein and 2.3% (2/88) experienced a failure rate in the embolization of the left gonadal vein. Of the 2 attempts at unilateral right-sided embolization, there were no failures. Of the 68 unilateral left-sided embolization attempts, there was a 4.4% failure rate. Of all of the right-sided embolization attempts, 18.9% failed, while 3.2% of the left-sided attempts failed.
: This review represents the largest contemporary series of varicocele embolization outcomes currently in the literature. Our 19.3% technical failure rate for bilateral varicocele embolization is higher than the current published rate of 13% and is largely related to failure to successfully occlude the right gonadal vein. This supports our belief that bilateral varicoceles are best managed with a primary microsurgical approach, where technical failure rates are expected to be less than 5% based on published data. Men with unilateral left-sided varicoceles should be offered both options as they have similar failure rates, but with embolization offering some clear advantages to the patient.
精索静脉曲张仍然是男性不育症中最常见的可纠正病因。手术矫正仍是治疗精索静脉曲张最常用的技术,技术失败率低于5%。一种有吸引力的手术替代方法是选择性性腺静脉导管插入术和栓塞术。但相关数据受限于小样本系列研究。
我们共回顾了158例患者。这些患者在2004年至2008年间因临床精索静脉曲张和男性不育症接受了栓塞治疗。其中,56%的患者尝试进行双侧栓塞,43%进行单侧左侧栓塞,1.3%进行单侧右侧栓塞。
在尝试进行双侧栓塞的患者中,19.3%的患者右侧性腺静脉未成功闭塞,2.3%(2/88)的患者左侧性腺静脉栓塞失败。在2次单侧右侧栓塞尝试中,无失败病例。在68次单侧左侧栓塞尝试中,失败率为4.4%。在所有右侧栓塞尝试中,18.9%失败,而左侧尝试中3.2%失败。
本综述是目前文献中关于精索静脉曲张栓塞治疗结果的最大规模当代系列研究。我们双侧精索静脉曲张栓塞的19.3%的技术失败率高于目前公布的13%,且主要与未能成功闭塞右侧性腺静脉有关。这支持了我们的观点,即双侧精索静脉曲张最好采用原发性显微手术方法治疗,根据已发表的数据,该方法的技术失败率预计低于5%。单侧左侧精索静脉曲张的患者应提供这两种选择,因为它们的失败率相似,但栓塞对患者有一些明显优势。