Specialist for Internal Medicine, Endocrinology and Diabetes, Sachsenhausen Hospital, Frankfurt/ Main, Germany.
Diabetes Metab Syndr Obes. 2012;5:357-67. doi: 10.2147/DMSO.S28340. Epub 2012 Oct 12.
The alpha-glucosidase inhibitor acarbose has been used for more than 20 years in the management of hyperglycemia. Owing to its unique mode of action in the gastrointestinal tract, its properties are very different from other antidiabetic medications. Patients on long-term treatment to control a chronic disease are not only interested in good treatment efficacy, but are also even more interested in the safety and side effects of their medications. Significant aspects of acarbose predominantly regarding safety and tolerability in the management of type 2 diabetes and prediabetes are reviewed. It is concluded that acarbose is a convenient long-term treatment option, with benefits for both type 2 diabetics and patients in a prediabetic state.
α-葡萄糖苷酶抑制剂阿卡波糖在治疗高血糖方面已经使用了 20 多年。由于其在胃肠道中的独特作用模式,其性质与其他抗糖尿病药物有很大的不同。长期接受治疗以控制慢性疾病的患者不仅对良好的治疗效果感兴趣,而且对药物的安全性和副作用更感兴趣。本文主要综述了阿卡波糖在 2 型糖尿病和糖尿病前期治疗中的安全性和耐受性方面的重要方面。结论是阿卡波糖是一种方便的长期治疗选择,对 2 型糖尿病患者和糖尿病前期患者都有好处。