J Pediatr Ophthalmol Strabismus. 2020 Sep 1;57(5):333-339. doi: 10.3928/01913913-20200804-01.
To describe a process for identifying birth weight (BW) and gestational age (GA) screening guidelines in Mongolia.
This was a prospective cohort study in a tertiary care hospital in Ulaanbataar, Mongolia, of 193 premature infants with GA of 36 weeks or younger and/or BW of 2,000 g or less) with regression analysis to determine associations between BW and GA and the development of retinopathy of prematurity (ROP).
As BW and GA decreased, the relative risk of developing ROP increased. The relative risk of developing any stage of ROP in infants born at 29 weeks or younger was 2.91 (95% CI: 1.55 to 5.44; P < .001] compared to older infants. The relative risk of developing any type of ROP in infants with BW of less than 1,200 g was 2.41 (95% CI: 1.35 to 4.29; P = .003] and developing type 2 or worse ROP was 2.05 (95% CI: 0.99 to 4.25; P = .05).
Infants in Mongolia with heavier BW and older GA who fall outside of current United States screening guidelines of GA of 30 weeks or younger and/or BW of 1,500 g or less developed clinically relevant ROP. [J Pediatr Ophthalmol Strabismus. 2020;57(5):333-339.].
描述蒙古制定出生体重(BW)和胎龄(GA)筛查指南的过程。
这是蒙古乌兰巴托一家三级保健医院的前瞻性队列研究,共纳入 193 名 GA 为 36 周或更小和/或 BW 为 2000 克或更小的早产儿,采用回归分析确定 BW 和 GA 与早产儿视网膜病变(ROP)之间的关系。
随着 BW 和 GA 的降低,发生 ROP 的相对风险增加。29 周或更小胎龄出生的婴儿发生任何阶段 ROP 的相对风险为 2.91(95%CI:1.55 至 5.44;P<.001),与年龄较大的婴儿相比。BW 小于 1200 克的婴儿发生任何类型 ROP 的相对风险为 2.41(95%CI:1.35 至 4.29;P=.003),发生 2 型或更严重 ROP 的相对风险为 2.05(95%CI:0.99 至 4.25;P=.05)。
蒙古的 BW 较重、GA 较大的婴儿,超出了目前美国 GA 为 30 周或更小和/或 BW 为 1500 克或更小的筛查指南,发生了有临床意义的 ROP。[J Pediatr Ophthalmol Strabismus. 2020;57(5):333-339]。