Liver Failure Group, UCL Institute for Liver and Digestive Health, University College London Medical School, London, UK.
Blood Purif. 2012;34(2):158-63. doi: 10.1159/000342065. Epub 2012 Oct 24.
Mortality of patients with liver failure remains unacceptably high. As the liver has an enormous potential to regenerate, extracorporeal liver support devices may allow patients with liver failure to be bridged to recovery. Alternatively, liver assist may allow patients with advanced liver disease to be managed until a suitable organ for transplant is available. Current approaches to liver support include the use of biological devices that contain hepatocytes and those that function as detoxification devices, and artificial liver support systems. This review describes the current state of the art and existing data on the use of these devices to treat patients with liver failure.
肝功能衰竭患者的死亡率仍然高得令人无法接受。由于肝脏具有巨大的再生潜力，体外肝脏支持设备可能使肝功能衰竭患者得以恢复。或者，肝脏辅助治疗可以使晚期肝病患者得到控制，直到有合适的移植器官可用。目前的肝脏支持方法包括使用含有肝细胞的生物装置和作为解毒装置的装置，以及人工肝脏支持系统。这篇综述描述了这些设备用于治疗肝功能衰竭患者的最新技术和现有数据。
