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盆腔器官脱垂的患病率、危险因素和预测因素:一项基于社区的研究。

Prevalence, risk factors, and predictors of pelvic organ prolapse: a community-based study.

机构信息

Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

Menopause. 2012 Nov;19(11):1235-41. doi: 10.1097/gme.0b013e31826d2d94.

Abstract

OBJECTIVE

This study aimed to determine the prevalence of pelvic organ prolapse (POP) in a village in East Lebanon and to evaluate related risk factors and clinical predictors.

METHODS

Five hundred four ever-married women, aged 15 to 60 years, were interviewed and underwent physical and pelvic examinations and laboratory testing. Prolapse was determined according to a simplified version of the POP quantification system.

RESULTS

Two hundred fifty-one (49.8%) women had clinically significant POP. When stratified by life decade, POP prevalence was 20.4% for women aged 20 to 29 years, 50.3% for women aged 30 to 39 years, 77.2% for women aged 40 to 49 years, and 74.6% for women aged 50 to 59 years, suggesting a plateau in prevalence in the decade after menopause. Clinically significant POP was found in 3.6% of nulliparous, 6.5% of primiparous, 22.7% of secondiparous, 32.9% of triparous, and 46.8% of tetraparous women. Increasing age, increasing vaginal parity, and a body mass index higher than 24 kg/m were found to be significant risk factors for POP, with relative risks of 1.09 (P < 0.001), 2.31 (P < 0.0001), and 1.62 (P = 0.048) respectively. Combined clinical symptoms of pelvic heaviness, urinary disturbances, and a feeling of bulge in the vagina were predictive of POP.

CONCLUSIONS

Our findings suggest that cost-efficient interventions to reduce the burden of POP in this and similar remote communities include the following: family planning awareness campaigns focusing on the risks of grand multiparity; nutritional education and weight management programs to help reduce the progression of POP before the age of menopause; and consideration of symptom-based screening to identify affected women who might benefit from a referral to specialty care at a tertiary care center.

摘要

目的

本研究旨在确定东黎巴嫩一个村庄中盆腔器官脱垂(POP)的患病率,并评估相关的危险因素和临床预测因素。

方法

对 504 名已婚、年龄在 15 至 60 岁的女性进行访谈和体格检查及盆腔检查,并进行实验室检查。脱垂根据简化的 POP 量化系统确定。

结果

251 名(49.8%)女性患有临床显著的 POP。按生活十年分层,20 至 29 岁女性的 POP 患病率为 20.4%,30 至 39 岁女性为 50.3%,40 至 49 岁女性为 77.2%,50 至 59 岁女性为 74.6%,提示绝经后十年患病率趋于平稳。在未生育、初产妇、经产妇、经产妇和经产妇中,临床显著 POP 的发生率分别为 3.6%、6.5%、22.7%、32.9%和 46.8%。年龄增长、阴道分娩次数增加和 BMI 高于 24kg/m2 是 POP 的显著危险因素,相对风险分别为 1.09(P<0.001)、2.31(P<0.0001)和 1.62(P=0.048)。盆腔沉重、尿失禁和阴道膨出感等联合临床症状是 POP 的预测因素。

结论

我们的研究结果表明,在这种和类似的偏远社区,以成本效益为基础的干预措施可以减少 POP 的负担,包括以下内容:以经产妇多育风险为重点的计划生育意识宣传;营养教育和体重管理计划,以帮助在绝经前减缓 POP 的进展;并考虑基于症状的筛查,以确定可能受益于转诊到三级保健中心的受影响妇女。

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