Department of Gynecology, Shaanxi Provincial People's Hospital, Xi'an, 710068, People's Republic of China.
School of Mechanical and Electrical Engineering, Xi'an University of Architecture and Technology, Xi'an, 710055, People's Republic of China.
Sci Rep. 2023 Mar 28;13(1):5082. doi: 10.1038/s41598-023-32368-z.
Uterine prolapse is a common gynecological disease, which seriously affects the quality of life and physical and mental health of elderly women. The aim of this study was to analyze the influence of different conditions (intra-abdominal pressure (IAP) and posture) on stress and displacement of uterine ligaments using the finite element method, and evaluate the contribution of uterine ligaments on uterus. The three-dimensional (3D) models of retroverted uterus and its accessory ligaments were established, loads and constraints were set in ABAQUS software, and the stress and displacement of uterine ligaments were calculated. The uterine displacement increased with the increase of IAP, and then the stress and displacement of each uterine ligament also increased. The uterine displacement was in the order of forward < upright < backward with different postures, and USL, CL and RL got larger values when the body was backward, while BL got a larger value when the body was forward. With the same condition, the stress of the uterine ligaments was in the order of USL > BL > CL > RL, and the displacement of the ligaments was in the order of BL > RL > USL > CL. The contribution of each uterine ligament changing with different IAP and postures was studied through finite element analysis, and the research results were consistent with the clinical data, which can provide a basis for exploring the mechanism of uterine prolapse.
子宫脱垂是一种常见的妇科疾病,严重影响老年妇女的生活质量和身心健康。本研究旨在采用有限元法分析不同条件(腹内压(IAP)和姿势)对子宫韧带的应力和位移的影响,并评估子宫韧带对子宫的贡献。建立了子宫后倾和其附属韧带的三维(3D)模型,在 ABAQUS 软件中设置了载荷和约束,并计算了子宫韧带的应力和位移。随着 IAP 的增加,子宫位移增加,然后各子宫韧带的应力和位移也增加。在不同的姿势下,子宫的位移顺序为前倾<直立<后倾,当身体向后倾斜时,USL、CL 和 RL 获得更大的值,而当身体向前倾斜时,BL 获得更大的值。在相同条件下,子宫韧带的应力顺序为 USL>BL>CL>RL,韧带的位移顺序为 BL>RL>USL>CL。通过有限元分析研究了不同 IAP 和姿势下各子宫韧带的变化情况,研究结果与临床数据一致,可为探讨子宫脱垂的发病机制提供依据。