University of Bath, UK.
Chem Commun (Camb). 2012 Dec 11;48(95):11626-8. doi: 10.1039/c2cc37427g.
Zirconocene dichloride (Cp(2)ZrCl(2)) has been shown to be an effective catalyst for the transamidation of primary amides with amines in cyclohexane at 80 °C in 5-24 hours. For favourable substrates, the reaction can be performed at temperatures as low as 30 °C.
二氯二茂锆(Cp(2)ZrCl(2))已被证明是一种有效的催化剂,可在 80°C 的环己烷中于 5-24 小时内实现伯酰胺与胺的转酰胺化反应。对于有利的底物,反应可以在低至 30°C 的温度下进行。