Papalia Teresa, Greco Rosita, Lofaro Danilo, Mollica Agata, Roberti Rita, Bonofiglio Renzo
Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, Cosenza - Italy.
J Nephrol. 2013 Sep-Oct;26(5):899-905. doi: 10.5301/jn.5000235. Epub 2012 Oct 24.
Among children, obesity and overweight may be predictors of cardiovascular (CV) risk. The purpose of this study was to examine whether body mass index (BMI), waist circumference (WC) and waist to height ratio (WHtR) were related to blood pressure (BP) among healthy southern Italian students enrolled in 3 different secondary schools.
Weight, height, BP and WC were measured; BMI and WHtR were calculated for 872 Italian students. Based on percentiles of BMI, the subjects were classified as underweight, normal weight, overweight or obese. Systolic BP or diastolic BP >95th percentile were considered as high BP values (according to the 2004 guidelines of the US National Heart, Lung, and Blood Institute). Central obesity was defined as WC >75th percentile or WHtR =0.5.
Of the students, 8.7% were obese, 29% with WC >75th percentile and 29.5% with WHtR >0.5, while 4.6% showed high BP. Logistic regression showed a strong correlation between BMI and high BP (odds ratio [OR] = 1.030, p<0.0001), between WC and high BP (OR = 1.029, p<0.0001). Also WHtR (OR = 3.403, p<0.0001) was shown to be a predictor of high BP. In the male group, all of the variables considered showed a good capability to predict high BP, while in the females, only BMI (OR = 1.019, p<0.05) and WHtR (OR = 2.685, p<0.05) were associated with high BP.
In this study, we found a different correlation between BMI, WC and BP in the 2 subgroups: males and females. Only WHtR showed a significant ability to predict high BP in both groups. WHtR might represent an easily measurable anthropometric index and a better predictor of CV risk in adolescents.
在儿童中，肥胖和超重可能是心血管（CV）风险的预测指标。本研究的目的是探讨在就读于3所不同中学的意大利南部健康学生中，体重指数（BMI）、腰围（WC）和腰高比（WHtR）是否与血压（BP）相关。
测量体重、身高、血压和腰围；计算872名意大利学生的BMI和WHtR。根据BMI百分位数，将受试者分为体重过轻、正常体重、超重或肥胖。收缩压或舒张压>第95百分位数被视为高血压值（根据美国国家心肺血液研究所2004年指南）。中心性肥胖定义为腰围>第75百分位数或腰高比=0.5。
学生中，8.7%为肥胖，29%腰围>第75百分位数，29.5%腰高比>0.5，而4.6%血压高。逻辑回归显示BMI与高血压之间存在强相关性（比值比[OR]=1.030，p<0.0001），WC与高血压之间存在强相关性（OR=1.029，p<0.0001）。腰高比（OR=3.403，p<0.0001）也被证明是高血压的预测指标。在男性组中，所有考虑的变量都显示出良好的预测高血压的能力，而在女性组中，只有BMI（OR=1.019，p<0.05）和腰高比（OR=2.685，p<0.05）与高血压相关。
在本研究中，我们发现BMI、WC与血压在两个亚组（男性和女性）之间存在不同的相关性。只有腰高比在两组中都显示出显著的预测高血压的能力。腰高比可能是一个易于测量的人体测量指标，也是青少年心血管风险的更好预测指标。
