Khoury Michael, Manlhiot Cedric, Dobbin Stafford, Gibson Don, Chahal Nita, Wong Helen, Davies Jolie, Stearne Karen, Fisher Amanda, McCrindle Brian W
Division of Cardiology, Labatt Family Heart Centre, Department of Pediatrics, University of Toronto, the Hospital for Sick Children, Toronto, Ontario, Canada.
Arch Pediatr Adolesc Med. 2012 Aug;166(8):719-24. doi: 10.1001/archpediatrics.2012.126.
To determine if the interaction of waist circumference percentile and waist to height ratio(WHtR) with body mass index (BMI) may serve to provide further risk specification in the lipid and blood pressure assessment of adolescents beyond BMI classification.
Population-based, cross-sectional study. Data collected during the 2009-2010 academic school year.
Geographically and administratively defined Niagara Region, Ontario, Canada. Data collected in school, during subjects’ mandatory physical education class. Part of the Heart Niagara Inc Healthy Heart Schools’ Program.
Entire population of grade 9 (14- and 15-year-old) students in the Niagara Region, Ontario.Four thousand eight hundred eighty-four students enrolled in grade 9 during the study period, of which 4104 participated (51% male) and 3248 (79%) had complete data.
Nonfasting lipid values and blood pressure categories in subjects categorized based on BMI/waist circumference percentile and BMI/WHtR.
The associations between blood pressure, lipid profile, and measures of adiposity (BMI alone, BMI/waist circumference percentile, and BMI/WHtR) were statistically significant but had a limited strength and were not statistically significant from each other. For overweight and obese subjects, increased WHtR categories were associated with worsened lipid profile and increased odds of hypertension both relative to subjects with both normal BMI and normal WHtR and subjects with normal WHtR within each BMI category.
Waist measures should be included in the screening and assessment of overweight and obese adolescents.
确定腰围百分位数和腰高比（WHtR）与体重指数（BMI）的相互作用是否有助于在青少年的血脂和血压评估中，在BMI分类之外进一步细化风险。
基于人群的横断面研究。数据收集于2009 - 2010学年。
加拿大安大略省地理和行政上界定的尼亚加拉地区。在学校，于受试者的必修体育课期间收集数据。是尼亚加拉心脏健康学校项目的一部分。
安大略省尼亚加拉地区所有九年级（14和15岁）学生。在研究期间，4884名学生注册进入九年级，其中4104名参与（51%为男性），3248名（79%）有完整数据。
根据BMI/腰围百分位数和BMI/WHtR分类的受试者的非空腹血脂值和血压类别。
血压、血脂谱与肥胖指标（单独的BMI、BMI/腰围百分位数和BMI/WHtR）之间的关联具有统计学意义，但强度有限，且彼此之间无统计学差异。对于超重和肥胖受试者，相对于BMI和WHtR均正常的受试者以及每个BMI类别中WHtR正常的受试者，WHtR类别增加与血脂谱恶化和高血压几率增加相关。
在超重和肥胖青少年的筛查和评估中应纳入腰围测量。
