Department of Rehabilitation, Nutrition and Sport, College of Science, Health and Engineering, La Trobe University, Bundoora, VIC, 3086, Australia.
Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens, Greece.
J Hum Hypertens. 2018 Mar;32(3):190-196. doi: 10.1038/s41371-018-0031-8. Epub 2018 Feb 6.
Excess body weight and fat mass levels in children have previously been associated with childhood hypertension. The aim of the current study was to identify anthropometric and body composition indices most strongly associated with hypertension and to propose relevant cut-off values for these indices, above which the likelihood of hypertension in schoolchildren aged 9-13 years old is increased. A sample of 2,665 children participated in a cross-sectional epidemiological study, the Healthy Growth Study. The current study enrolled 1,315 children with full data on blood pressure, anthropometric, and body composition indices. Increased blood pressure in children was associated with body mass index (BMI) (odds ratio (OR) 1.188), waist circumference (OR 1.062), waist-to-height ratio (OR 1.101), total body fat mass (OR 1.063), and trunk fat mass levels (OR 1.083). Also, BMI, waist circumference, waist-to-height ratio, trunk fat mass, and total body fat mass levels above the age-specific and gender-specific cut-off values identified in the present study were associated with a higher likelihood of hypertension. Anthropometric and body composition indices and the relevant cut-off values proposed by the current study can be used for identifying children with higher likelihood of presence of hypertension, as the available BMI thresholds for identifying overweight and obese children may underestimate those at increased risk of hypertension. It is essential for future studies to confirm these findings.
先前已有研究表明,儿童超重和体脂水平与儿童高血压有关。本研究旨在确定与高血压相关性最强的人体测量和身体成分指标,并提出这些指标的相关临界值,以便在 9-13 岁学龄儿童中,高血压的可能性增加。有 2665 名儿童参与了横断面流行病学研究,即健康生长研究。本研究共纳入了 1315 名儿童,他们有完整的血压、人体测量和身体成分指标数据。儿童血压升高与体重指数(BMI)(比值比(OR)1.188)、腰围(OR 1.062)、腰高比(OR 1.101)、全身脂肪量(OR 1.063)和躯干脂肪量水平(OR 1.083)相关。此外,本研究确定的年龄和性别特异性临界值以上的 BMI、腰围、腰高比、躯干脂肪量和全身脂肪量水平与高血压的可能性增加相关。本研究提出的人体测量和身体成分指标及相关临界值可用于识别高血压可能性更高的儿童,因为现有的 BMI 阈值用于识别超重和肥胖儿童可能低估了那些高血压风险增加的儿童。未来的研究需要证实这些发现。