Norris M C
Department of Anesthesiology, Thomas Jefferson University, Philadelphia, Pennsylvania.
Anesthesiology. 1990 Mar;72(3):478-82. doi: 10.1097/00000542-199003000-00015.
To determine if age, height, weight, body mass index, or vertebral column length significantly influence the distribution of sensory analgesia or anesthesia after subarachnoid injection of hyperbaric bupivacaine, 52 women presenting for cesarean section were studied. All received 15 mg hyperbaric bupivacaine via subarachnoid injection at L-2 or L-3. Fifteen minutes after injection, while the women lay supine on a horizontal operating table, the maximum cephalad extent of sensory analgesia (loss of sensation of sharpness to pin prick) and anesthesia (loss of sensation of light touch) was determined. Age (20-42 yr), height (146.9-174.0 cm), weight (55.5-136.4 kg), body mass index (19.2-50.0 kg/m2), and vertebral column length (49.6-67.0 cm) did not correlate with the spread of sensory blockade. In conclusion, in parturients of age, height, weight, body mass index, and vertebral column length within the aforementioned ranges, it is not necessary to vary the dose of injected hyperbaric bupivacaine with changes in any of the patient variables studied.
为了确定年龄、身高、体重、体重指数或脊柱长度是否会显著影响蛛网膜下腔注射重比重布比卡因后感觉镇痛或麻醉的分布，对52例拟行剖宫产的女性进行了研究。所有患者均在L-2或L-3水平通过蛛网膜下腔注射15mg重比重布比卡因。注射后15分钟，当患者仰卧在水平手术台上时，测定感觉镇痛（对针刺锐痛感觉丧失）和麻醉（对轻触觉感觉丧失）的最大头侧范围。年龄（20 - 42岁）、身高（146.9 - 174.0厘米）、体重（55.5 - 136.4千克）、体重指数（19.2 - 50.0千克/平方米）和脊柱长度（49.6 - 67.0厘米）与感觉阻滞的范围无关。总之，对于年龄、身高、体重、体重指数和脊柱长度在上述范围内的产妇，无需根据所研究的任何患者变量的变化来改变重比重布比卡因的注射剂量。
