Swine Clinic, Vetsuisse Faculty, University of Bern, Bern 3001, Switzerland.
Vet Rec. 2012 Nov 17;171(20):503. doi: 10.1136/vr.101052. Epub 2012 Oct 25.
Immunisation of sows using Clostridium perfringens type C toxoid vaccines is recommended to prevent necrotising enteritis (NE) on pig breeding farms. Absence of disease, however, oftentimes leads to the false assumption of pathogens being eradicated. The prevalence of C perfringens type C was determined by PCR in faecal samples of piglets and sows in three Swiss pig breeding farms two to four years after implementation of a vaccination programme following disease outbreaks. C perfringens type C could still be detected several years after an outbreak despite absence of NE. In-herd prevalence of the pathogens varied significantly between the farms and was also lower compared with a farm which experienced a recent outbreak. In conclusion, C perfringens type C can be detected on once-affected farms, even in the absence of NE for several years.
在养猪场,推荐使用产气荚膜梭菌 C 型类毒素疫苗对母猪进行免疫接种,以预防坏死性肠炎(NE)。然而,疾病的不存在往往会导致人们错误地认为病原体已被根除。在疾病爆发后实施疫苗接种计划的两到四年后,通过对瑞士三个养猪场的仔猪和母猪的粪便样本进行 PCR 检测,确定了产气荚膜梭菌 C 型的流行情况。尽管没有发生 NE,但在爆发后数年仍能检测到产气荚膜梭菌 C 型。在这些农场中,病原体的场内流行率差异很大,并且也低于最近发生过爆发的农场。总之,即使在没有 NE 的情况下,产气荚膜梭菌 C 型也可以在曾经受影响的农场中被检测到,甚至可以持续数年。