那他珠单抗停药后发生致命性多发性硬化复发。 - Suppr

Lethal multiple sclerosis relapse after natalizumab withdrawal.

作者信息

Rigau Valérie, Mania Alexandre, Béfort Patrice, Carlander Bertrand, Jonquet Olivier, Lassmann Hans, Camu William, Thouvenot Eric

机构信息

Service d'Anatomopathologie, CHRU de Montpellier, Université Montpellier I, Montpellier, France.

出版信息

Neurology. 2012 Nov 27;79(22):2214-6. doi: 10.1212/WNL.0b013e318275979d. Epub 2012 Oct 24.

DOI:10.1212/WNL.0b013e318275979d

PMID:23100404

Abstract

摘要

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Lethal multiple sclerosis relapse after natalizumab withdrawal.那他珠单抗停药后发生致命性多发性硬化复发。

Neurology. 2012 Nov 27;79(22):2214-6. doi: 10.1212/WNL.0b013e318275979d. Epub 2012 Oct 24.

Clinical and radiological disease reactivation after cessation of long-term therapy with natalizumab.长期使用那他珠单抗治疗后临床和影像学疾病再激活。

Int J Neurosci. 2012 Jan;122(1):35-9. doi: 10.3109/00207454.2011.622452. Epub 2011 Oct 21.

Voxel-wise magnetization transfer imaging study of effects of natalizumab and IFNβ-1a in multiple sclerosis.体素磁化转移成像研究纳昔单抗和 IFNβ-1a 在多发性硬化中的作用。

Mult Scler. 2012 Aug;18(8):1125-34. doi: 10.1177/1352458511433304. Epub 2011 Dec 22.

Immune reconstitution inflammatory syndrome after withdrawal of natalizumab?停用那他珠单抗后发生的免疫重建炎症综合征？

Neurology. 2010 Aug 31;75(9):831-3. doi: 10.1212/WNL.0b013e3181f07362.

Dramatic worsening following plasma exchange in severe post-natalizumab withdrawal multiple sclerosis relapse.在产后纳武单抗停药后严重多发性硬化症复发中，进行血浆置换后病情急剧恶化。

Mult Scler. 2011 Dec;17(12):1520-2. doi: 10.1177/1352458511411064. Epub 2011 Jun 13.

Natalizumab remains detectable in patients with multiple sclerosis long after treatment is stopped.那他珠单抗在多发性硬化症患者停止治疗后很长时间仍可检测到。

Mult Scler. 2012 Jun;18(6):899-901. doi: 10.1177/1352458511431073. Epub 2011 Dec 19.

Risk of natalizumab-associated progressive multifocal leukoencephalopathy.纳武利尤单抗相关进行性多灶性白质脑病的风险。

N Engl J Med. 2012 May 17;366(20):1870-80. doi: 10.1056/NEJMoa1107829.

Natalizumab and drug holiday in clinical practice: an observational study in very active relapsing remitting multiple sclerosis patients.那他珠单抗和药物假期在临床实践中的应用：一项在非常活跃的复发缓解型多发性硬化症患者中的观察性研究。

J Neurol Sci. 2011 Sep 15;308(1-2):98-102. doi: 10.1016/j.jns.2011.05.043. Epub 2011 Jun 12.

Natalizumab for relapsing-remitting multiple sclerosis.那他珠单抗治疗复发缓解型多发性硬化。

Neurologia. 2011 Jul-Aug;26(6):357-68. doi: 10.1016/j.nrl.2010.10.004. Epub 2010 Dec 28.

Simultaneous PML-IRIS after discontinuation of natalizumab in a patient with MS.一名多发性硬化症患者停用那他珠单抗后同时发生进行性多灶性白质脑病合并免疫重建炎症综合征。

Neurology. 2012 Nov 20;79(21):2160; author reply 2160. doi: 10.1212/01.wnl.0000423208.11698.16.

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Maedica (Bucur). 2024 Dec;19(4):823-828. doi: 10.26574/maedica.2024.19.4.8232024;.

CD138 as a Specific CSF Biomarker of Multiple Sclerosis.CD138 作为多发性硬化症的特异性 CSF 生物标志物。

Neurol Neuroimmunol Neuroinflamm. 2024 May;11(3):e200230. doi: 10.1212/NXI.0000000000200230. Epub 2024 Apr 25.

Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound.由于那他珠单抗治疗增强了 Th17 细胞的致病性：对 MS 疾病反弹的影响。

Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2209944120. doi: 10.1073/pnas.2209944120. Epub 2022 Dec 27.

Multiple Sclerosis Disease Activity and Disability Following Discontinuation of Natalizumab for Pregnancy.多发性硬化症患者停止使用那他珠单抗后的疾病活动度和残疾状况与妊娠有关。

JAMA Netw Open. 2022 Jan 4;5(1):e2144750. doi: 10.1001/jamanetworkopen.2021.44750.

The results of a 24-month controlled, prospective study of relapsing multiple sclerosis patients at risk for progressive multifocal encephalopathy, who switched from prolonged use of natalizumab to teriflunomide.一项针对有进行性多灶性白质脑病风险的复发型多发性硬化症患者的24个月对照前瞻性研究结果，这些患者从长期使用那他珠单抗转而使用特立氟胺。

Mult Scler J Exp Transl Clin. 2021 Dec 16;7(4):20552173211066588. doi: 10.1177/20552173211066588. eCollection 2021 Oct.

The German Multiple Sclerosis and Pregnancy Registry: rationale, objective, design, and first results.德国多发性硬化症与妊娠登记处：基本原理、目标、设计及初步结果。

Ther Adv Neurol Disord. 2021 Nov 22;14:17562864211054956. doi: 10.1177/17562864211054956. eCollection 2021.

The CD8 T Cell-Epstein-Barr Virus-B Cell Trialogue: A Central Issue in Multiple Sclerosis Pathogenesis.CD8 T 细胞- Epstein-Barr 病毒-B 细胞对话：多发性硬化症发病机制中的一个核心问题。

Front Immunol. 2021 Jul 7;12:665718. doi: 10.3389/fimmu.2021.665718. eCollection 2021.

J Drug Assess. 2020 Jan 23;9(1):20-36. doi: 10.1080/21556660.2020.1721507. eCollection 2020.

Reducing return of disease activity in patients with relapsing multiple sclerosis transitioned from natalizumab to teriflunomide: 12-month interim results of teriflunomide therapy.从那他珠单抗转换为特立氟胺治疗的复发型多发性硬化症患者疾病活动度复发的降低：特立氟胺治疗12个月的中期结果

Mult Scler J Exp Transl Clin. 2019 Jan 16;5(1):2055217318824618. doi: 10.1177/2055217318824618. eCollection 2019 Jan-Mar.

Disease activity following pregnancy-related discontinuation of natalizumab in MS.多发性硬化症患者在与妊娠相关的那他珠单抗停药后的疾病活动情况。

Neurol Neuroimmunol Neuroinflamm. 2017 Dec 5;5(1):e424. doi: 10.1212/NXI.0000000000000424. eCollection 2018 Jan.

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Lethal multiple sclerosis relapse after natalizumab withdrawal.

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