Monell Chemical Senses Center, 3500 Market St., Philadelphia, PA 19104, USA.
J Hered. 2013 Mar;104(2):295-7. doi: 10.1093/jhered/ess089. Epub 2012 Oct 25.
The tf (tufted) locus is responsible for a classic phenotype of hair loss and regrowth in mice. It is a characteristic of the BTBR strain. Here, we use a combination of positional cloning methods and complementation mapping to identify Itpr3, the inositol triphosphate receptor type 3, as the gene responsible for the tf locus.
tf(簇毛)基因座负责小鼠的经典脱发和再生表型。它是 BTBR 品系的一个特征。在这里,我们使用定位克隆方法和互补作图的组合来鉴定肌醇三磷酸受体 3(Itpr3),它是负责 tf 基因座的基因。