Underner M, Perriot J, Trosini-Desert V, Ouedreaogo G, Peiffer G, Meurice J-C, Dautzenberg B
Unité de tabacologie, service de pneumologie, centre de lutte antituberculeuse (CLAT 86), CHU la Milétrie, pavillon René-Beauchant, 2, rue Milétrie, BP 577, 86021 Poitiers cedex, France.
Rev Mal Respir. 2012 Oct;29(8):1007-16. doi: 10.1016/j.rmr.2012.06.006. Epub 2012 Aug 11.
Tobacco smoking has a significant impact on the risk of tuberculosis and the mortality of the disease. There is a strong dose-response relationship both in terms of quantity and duration of smoking. Latent tuberculous infection and tuberculosis disease are different stages of the same infectious process but the relation between smoking and the risk of being infected with Mycobacterium tuberculosis is less well understood. The aim of this review is to describe the relationship between tobacco consumption and tuberculous infection and the mechanism by which smoking increases the risk. It outlines the public health consequences of the increased risk of latent tuberculous infection due to active and passive smoking. This justifies promotion of smoking cessation as a way of limiting the epidemic of tuberculosis in developing countries.
吸烟对结核病风险和该病死亡率有重大影响。在吸烟量和吸烟持续时间方面均存在很强的剂量反应关系。潜伏结核感染和结核病是同一感染过程的不同阶段，但吸烟与感染结核分枝杆菌风险之间的关系尚不太清楚。本综述的目的是描述烟草消费与结核感染之间的关系以及吸烟增加风险的机制。它概述了主动和被动吸烟导致潜伏结核感染风险增加所带来的公共卫生后果。这证明了促进戒烟作为限制发展中国家结核病流行的一种方式是合理的。
