Zhang Xing-Ru, Zhang Zhen-Yong, Hoffman Matthew R
Department of Ophthalmology, Putuo Hospital, Shanghai Chinese Traditional Medicine University, Shanghai, China.
Int Surg. 2012 Jan-Mar;97(1):90-3. doi: 10.9738/CC59.1.
The purpose of this study was to present a new procedure to treat symptomatic conjunctivochalasis (CCh) and to evaluate its efficacy. Forty-two patients with symptomatic CCh refractory to medical management were included on this study. Twenty-two patients (n = 32, eyes; n = 14 women and n = 8 men) underwent the new electrocoagulation procedure (group I). Twenty patients (n = 27 eyes; n = 11 women and n = 9 men) underwent crescent-shaped conjunctiva resection (group II). Ocular surface disease index (OSDI) was used to evaluate ocular symptoms. There was a significant difference in mean and SD operation time between group I (8.67 ± 2.07 minutes) and group II (20.45 ± 3.98 minutes; P < 0.0001). OSDI scores (mean ± SD) were significantly lower in group I (28.38 ± 3.14) than group II (31.62 ± 3.17) at postoperative week 2 (P = 0.0004). No differences in OSDI scores were found between the 2 groups at postoperative week 4 (P = 0.1749) or 8 (P = 0.1483). OSDI scores were significantly lower at postoperative week 8 than at baseline in both group I (P = 0.0002) and group II (P = 0.0011). Electrocoagulation of the conjunctiva can successfully treat symptomatic CCh with earlier symptomatic attenuation and less operation time than traditional conjunctiva resection.
本研究的目的是提出一种治疗症状性结膜松弛症(CCh)的新方法并评估其疗效。本研究纳入了42例经药物治疗无效的症状性CCh患者。22例患者(n = 32只眼;n = 14名女性和n = 8名男性)接受了新的电凝手术(I组)。20例患者(n = 27只眼;n = 11名女性和n = 9名男性)接受了新月形结膜切除术(II组)。采用眼表疾病指数(OSDI)评估眼部症状。I组(8.67±2.07分钟)和II组(20.45±3.98分钟;P<0.0001)的平均手术时间和标准差存在显著差异。术后第2周,I组(28.38±3.14)的OSDI评分(均值±标准差)显著低于II组(31.62±3.17)(P = 0.0004)。术后第4周(P = 0.1749)和第8周(P = 0.1483)两组的OSDI评分无差异。I组(P = 0.0002)和II组(P = 0.0011)术后第8周的OSDI评分均显著低于基线水平。结膜电凝术可成功治疗症状性CCh,与传统结膜切除术相比,症状缓解更早,手术时间更短。