Alaya A, Hellara I, Belgith M, Nouri A, Hellara W, Neffati F, Saad H, Najjar M F
Laboratoire de biochimie et de toxicologie, hôpital universitaire de Monastir, Monastir, Tunisie.
Prog Urol. 2012 Nov;22(15):938-44. doi: 10.1016/j.purol.2012.07.010. Epub 2012 Aug 30.
Studies that evaluated the effect of age and gender on the stone composition were scarce. The aim of this study was to identify the stone composition in Tunisian patients and to highlight their modification according to patients' sex and age.
We studied 1200 urolithiasic patients, from the urologic and the pediatric surgery departments, ranging from six months to 92years old and known as having urinary stones (729 males and 471 females). Stone analysis was performed respectively using a stereomicroscope and infrared spectroscopy to determine, respectively, the morphological type and the molecular composition of each.
Kidney stones were encountered in 48.6% of calculi. Children and old men were more affected by bladder stone. Whewellite was the main component in 51.8% of the stones and 39.6% of the stone core, its frequency fell according to age from 61.4% in young adults to 47.7% in elderly in favor of the increase of uric acid stones, from 16.4% in young adults to 35.6% in elderly (P<0,02). Struvite stones were rare (3.2%) and more frequent in boys.
The analysis of these data shows that urinary stones in Tunisia were tending to evolve in the same direction as in industrialized countries.
评估年龄和性别对结石成分影响的研究较少。本研究的目的是确定突尼斯患者的结石成分,并强调其根据患者性别和年龄的变化。
我们研究了来自泌尿外科和小儿外科的1200例尿路结石患者,年龄从6个月至92岁,均患有尿路结石(男性729例,女性471例)。分别使用体视显微镜和红外光谱进行结石分析,以确定每种结石的形态类型和分子组成。
48.6%的结石为肾结石。儿童和老年男性更容易患膀胱结石。水草酸钙是51.8%的结石和39.6%的结石核心的主要成分,其频率随年龄下降,从年轻人中的61.4%降至老年人中的47.7%,有利于尿酸结石的增加,从年轻人中的16.4%增至老年人中的35.6%(P<0.02)。磷酸铵镁结石罕见(3.2%),在男孩中更常见。
对这些数据的分析表明,突尼斯的尿路结石发展趋势与工业化国家相同。