Department of Urology, School of Medicine, Rize University, Rize, Turkey.
Urology. 2012 Dec;80(6):1283-6. doi: 10.1016/j.urology.2012.08.029. Epub 2012 Oct 24.
To identify autonomic nervous dysfunction in patients with lifelong premature ejaculation.
The study participants were 25 men with lifelong premature ejaculation and 25 healthy controls. The parameters of 24-hour heart rate variability that are influenced by the autonomic nervous system were compared between the men with lifelong premature ejaculation and the healthy controls.
The laboratory results of all patients were within normal limits, and no significant differences were found between the patients and the controls in age, body weight, and body mass index. A low-frequency signal that is influenced by the sympathetic system was increased in the patients (P = .026). Furthermore, a high-frequency signal that is influenced by the parasympathetic system was decreased in the patients (P = .011). Finally, the low frequency-to-high frequency ratio, an indicator of the balance between the two components of the autonomic nervous system, was increased in the patients (P = .002).
To our knowledge, no study has investigated the influence of the autonomic nervous system on 24-hour heart rate variability in premature ejaculation. In the present study, sympathetic activity was increased in men with lifelong premature ejaculation; this overactivity might lead to lifelong premature ejaculation. Additional studies are required to reveal the possible alteration of the autonomic nervous system in premature ejaculation.
识别早泄患者的自主神经功能障碍。
研究对象为 25 名有终身早泄的男性和 25 名健康对照者。比较了终身早泄男性和健康对照组之间受自主神经系统影响的 24 小时心率变异性的参数。
所有患者的实验室结果均在正常范围内，患者与对照组在年龄、体重和体重指数方面无显著差异。受交感系统影响的低频信号在患者中增加（P=0.026）。此外，受副交感系统影响的高频信号在患者中减少（P=0.011）。最后，自主神经系统两个组成部分之间平衡的低频与高频比在患者中增加（P=0.002）。
据我们所知，尚无研究调查自主神经系统对早泄患者 24 小时心率变异性的影响。在本研究中，终身早泄男性的交感活动增加；这种过度活动可能导致终身早泄。需要进一步的研究来揭示早泄中自主神经系统可能发生的改变。
