From the Rothschild Foundation (Guedj, Saad, Audureau, Gatinel), Hôpital Cochin-Hôtel Dieu (Guedj), and Center for Expertise and Research in Optics for Clinicians (Saad, Audureau, Gatinel), Paris, France.
From the Rothschild Foundation (Guedj, Saad, Audureau, Gatinel), Hôpital Cochin-Hôtel Dieu (Guedj), and Center for Expertise and Research in Optics for Clinicians (Saad, Audureau, Gatinel), Paris, France.
J Cataract Refract Surg. 2013 Jan;39(1):66-73. doi: 10.1016/j.jcrs.2012.08.058. Epub 2012 Oct 24.
To assess the long-range outcomes of photorefractive keratectomy (PRK) using functional and topographic criteria in myopic eyes with suspected keratoconus.
Rothschild Foundation, Paris, France.
Retrospective interventional case series.
Eyes of patients classified as keratoconus suspects or keratoconus by the Corneal Navigator software of the OPD-Scan II device were included. They were treated with myopic PRK using an EC-5000 excimer laser between 2004 and 2007. The main outcome measures were refractive stability, mean corneal keratometry, mean central pachymetry, mean thinnest point value, and the occurrence of postoperative complications such as corneal ectasia.
The study evaluated 62 eyes of 42 patients. The mean patient age was 34.6 years ± 15.1 (SD) and the mean spherical equivalent (SE), -3.96 ± 3.05 diopters (D). The mean central pachymetry was 529.4 ± 32.8 μm and the mean simulated keratometry, 45.75 ± 1.75 D. The percentage of similarity to keratoconus suspects or keratoconus was positive in all 62 eyes and exceeded a 50% similarity score in 30 eyes (48.4%). The mean follow-up was 4.8 ± 1.4 years. The mean magnitude of the SE was -0.53 ± 1.35 D over the follow-up. Two patients required glasses postoperatively because of significant myopic regression. No case of corneal ectasia was reported.
Photorefractive keratectomy in eyes with suspected keratoconus based on a Placido neural network may be safe and effective for myopia and astigmatism in carefully selected patients.
使用功能和地形标准评估疑似圆锥角膜的近视眼中的光折射性角膜切削术（PRK）的长期结果。
法国巴黎 Rothschild 基金会。
回顾性干预性病例系列。
包括使用 OPD-Scan II 设备的角膜导航仪软件分类为疑似圆锥角膜或圆锥角膜的患者的眼睛。这些眼睛在 2004 年至 2007 年间使用 EC-5000 准分子激光接受近视 PRK 治疗。主要观察指标为屈光稳定性、平均角膜曲率、平均中央角膜厚度、平均最薄点值以及术后并发症（如角膜扩张）的发生。
本研究评估了 42 名患者的 62 只眼。患者的平均年龄为 34.6 岁±15.1（标准差），平均球镜等效值（SE）为-3.96±3.05 屈光度（D）。平均中央角膜厚度为 529.4±32.8μm，平均模拟角膜曲率为 45.75±1.75D。62 只眼中所有眼的与疑似圆锥角膜或圆锥角膜的相似度百分比均为阳性，其中 30 只眼（48.4%）相似度超过 50%。平均随访时间为 4.8±1.4 年。随访期间 SE 的平均大小为-0.53±1.35D。由于明显的近视回退，有 2 名患者术后需要戴眼镜。未报告角膜扩张病例。
基于 Placido 神经网络的疑似圆锥角膜患者的光折射性角膜切削术对于仔细选择的患者的近视和散光可能是安全有效的。
