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阿萨姆人群血脂谱参考区间的估计。

Stimation of reference interval of lipid profile in Assamese population.

作者信息

Das Madhumita, Saikia Mauchumi

机构信息

Department of Pathology, Guwahati Neurological Research Center, Guwahati, India.

出版信息

Indian J Clin Biochem. 2009 Apr;24(2):190-3. doi: 10.1007/s12291-009-0034-x. Epub 2009 Jul 9.

Abstract

12hrs fasting samples of 1485 apparently healthy, Assamese population in the age group of 20-80 yrs., mostly from the urban area of Assam were tested for serum lipid profile that includes total cholesterol, triacylglycerol, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C) over a period of three years. The values (median and range in mg/dl) obtained were 170 (93-263); 110 (40-256); 40 (23-73); 103 (40-173) and 22 (8-51) respectively. After grouping these subjects according to the age and sex no significant difference were observed between most of the groups. Median and upper range of total cholesterol, HDL-C and LDL-C were found to be higher in women than in men in all the age groups. But triacylglycerol and VLDL-C concentrations were observed to be higher in the men than women except in age group of 61-70 yrs. It can be suggested that lipid values obtained in this study can be used as the reference value, based on which clinical correlation can be made.

摘要

在三年时间里,对1485名年龄在20至80岁之间、显然健康的阿萨姆族人群(大多来自阿萨姆邦市区)的12小时空腹样本进行了血清脂质谱检测,检测项目包括总胆固醇、三酰甘油、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和极低密度脂蛋白胆固醇(VLDL-C)。所获得的值(以mg/dl为单位的中位数和范围)分别为170(93 - 263);110(40 - 256);40(23 - 73);103(40 - 173)和22(8 - 51)。在根据年龄和性别对这些受试者进行分组后,大多数组之间未观察到显著差异。在所有年龄组中,发现女性的总胆固醇、HDL-C和LDL-C的中位数及上限均高于男性。但除61 - 70岁年龄组外,观察到男性的三酰甘油和VLDL-C浓度高于女性。可以认为,本研究中获得的脂质值可作为参考值,在此基础上可进行临床相关性分析。

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