Department of Preventive and Community Dentistry, Oral Health Research Institute, Indiana University School of Dentistry, Indianapolis, IN 46202, USA.
Caries Res. 2013;47(1):50-5. doi: 10.1159/000343164. Epub 2012 Oct 25.
Acid gel caries lesions were created in 3,100 human and bovine enamel specimens and studied with transverse microradiography. Small, significant differences were found. Human enamel lesions were found to be less demineralized, shallower, had a higher ratio of integrated mineral loss (ΔZ) to lesion depth (L), a lower degree of surface zone mineralization (SZ(max)) and showed less variability than those in bovine enamel. SZ(max) showed the highest variability. Between tissues, L differed the most, ΔZ the least. Biological variation within bovine enamel is perhaps not only bigger than previously assumed, it may also overshadow any structural and chemical differences between tissues.
采用横切式显微放射摄影术对 3000 个人类和牛牙釉质标本的酸性凝胶龋损进行了研究。结果发现了一些微小但显著的差异。与牛牙釉质相比,人类牙釉质的龋损脱矿程度较低、深度较浅,其矿物质总丢失量(ΔZ)与龋损深度(L)的比值较高,表面区域矿化程度(SZ(max))较低,且变异性较小。SZ(max)的变异性最高。在不同组织中,L 的差异最大,ΔZ 的差异最小。牛牙釉质内部的生物学变异性可能不仅比之前假设的更大,而且可能掩盖了组织之间的任何结构和化学差异。