Department of Restorative Dentistry, São Paulo State University - UNESP, Institute of Science and Technology, Av. Eng. Francisco Jose Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
Department of Dental Materials and Prosthodontics, São Paulo State University - UNESP, Institute of Science and Technology, Av. Eng. Francisco Jose Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
Sci Rep. 2020 Nov 4;10(1):18992. doi: 10.1038/s41598-020-76127-w.
This study evaluated the efficacy of S-PRG vanishes on preventing enamel demineralization. Bovine enamel specimens were obtained, polished and the baseline Knoop microhardness was evaluated. Specimens were stratified into six groups (n = 15), according to the varnish applied: S10-experimental varnish containing 10% of S-PRG fillers, S20-20% of S-PRG fillers, S30-30% of S-PRG fillers; S40-40% of S-PRG fillers; PC (positive control)-5% of NaF; NC (negative control)-no treatment was performed. Half of enamel surfaces were protected to work as a control and varnishes were applied over the unprotected area. A demineralizing pH-cycling was performed, and surface and cross-sectional microhardness were measured. The percentage of microhardness of the treated area was calculated comparing with the untreated area. Statistical analysis was performed by one-way ANOVA and Tukey's test (p = 5%). All experimental S-PRG varnishes protected against demineralization in relation to no treatment, but S40 was the most effective on the surface. For all depths, S30 and S40 were superior in enamel demineralization prevention than other S-PRG filler concentrations and 5% NaF. It was concluded that S-RPG filler containing varnishes were effective to prevent enamel demineralization. The higher concentrated products were more effective than 5% sodium fluoride on surface demineralization prevention.
本研究评估了 S-PRG 消失物预防牙釉质脱矿的功效。获得牛牙釉质标本，抛光后评估基线 Knoop 显微硬度。根据应用的清漆将标本分为六组（n=15）：S10-含有 10% S-PRG 填料的实验清漆、S20-20% S-PRG 填料、S30-30% S-PRG 填料、S40-40% S-PRG 填料；PC（阳性对照）-5% NaF；NC（阴性对照）-不进行处理。一半的牙釉质表面受到保护作为对照，未保护区域涂有清漆。进行脱矿 pH 循环，并测量表面和横截面显微硬度。通过比较未处理区域来计算处理区域的显微硬度百分比。通过单向方差分析和 Tukey 检验进行统计分析（p=5%）。所有实验 S-PRG 清漆都能防止脱矿，与不处理相比，但 S40 在表面上最有效。对于所有深度，S30 和 S40 在预防牙釉质脱矿方面均优于其他 S-PRG 填料浓度和 5%氟化钠。结论是含有 S-RPG 填料的清漆能有效预防牙釉质脱矿。高浓度产品在预防表面脱矿方面比 5%氟化钠更有效。
