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治疗压力性尿失禁的新手术技术TVT-ABBREVO:从研发到临床经验

New surgical technique for treatment of stress urinary incontinence TVT-ABBREVO from development to clinical experience.

作者信息

Waltregny David, de Leval Jean

机构信息

Department of Urology, University Hospital of Liège, Liège, Belgium.

出版信息

Surg Technol Int. 2012 Dec;22:149-57.

Abstract

Tension-free suburethral tapes have revolutionized the surgical treatment of female stress urinary incontinence (SUI). These tapes are inserted by way of a retropubic or transobturator route. The inside-out tension-free vaginal tape transobturator approach, or TVT-Obturator system (TVT-O, Ethicon Women's Health and Urology, Somerville, NJ), was developed ten years ago with the aim of minimizing the risk of urinary tract injuries associated with retropubic and outside-in transobturator tapes while reproducibly ensuring minimal tissue dissection. Cadaveric studies have shown that the anatomical trajectory of the TVT-O tape is strictly perineal and courses away from neighboring obturator and pudendal neurovascular structures. Several meta-analyses have shown similar SUI cure rates after retropubic and transobturator tape procedures. Yet, the transobturator route may be associated with less voiding dysfunction, blood loss, bladder perforation, and shorter operating time. The original TVT-O procedure was modified with the aim of reducing the incidence of postoperative groin pain as well as the rather theoretical risk of obturator nerve injury. This modified procedure, named TVT-ABBREVO (Ethicon Women's Health and Urology, Somerville, NJ), utilizes a shortened, 12-cm-long polypropylene tape. In addition, perforation of the obturator membrane with the scissors and guide is avoided in order to reduce the depth of lateral dissection, and consequently, to maximize securing of the tape within the obturator muscular/aponeurotic structures. In a comparative anatomical study, it was indeed observed that the shorter tape traversed less muscular structures (with no or only a minimal amount of tape lying in the adductor muscles) than its original counterpart, while still consistently anchoring in the obturator membrane at a similarly safe distance from the obturator canal. In a single-center randomized clinical trial, after a 3-year minimum follow-up, the modified TVT-O procedure with a shorter tape and reduced dissection was found to be as safe and efficient as the primal procedure for treating female SUI, with less severe and frequent groin pain in the immediate postoperative period.

摘要

无张力尿道下吊带彻底改变了女性压力性尿失禁(SUI)的外科治疗方法。这些吊带通过耻骨后或经闭孔途径插入。由内向外的无张力阴道吊带经闭孔入路,即TVT-闭孔系统(TVT-O,美国新泽西州萨默维尔市爱惜康女性健康与泌尿外科公司),于十年前研发,目的是将与耻骨后和由外向内经闭孔吊带相关的尿路损伤风险降至最低,同时确保可重复性地减少组织解剖。尸体研究表明,TVT-O吊带的解剖轨迹严格位于会阴区,且远离相邻的闭孔和阴部神经血管结构。多项荟萃分析显示,耻骨后和经闭孔吊带手术后的SUI治愈率相似。然而,经闭孔途径可能与较少的排尿功能障碍、失血、膀胱穿孔以及更短的手术时间相关。最初的TVT-O手术进行了改良,旨在降低术后腹股沟疼痛的发生率以及理论上的闭孔神经损伤风险。这种改良手术名为TVT-ABBREVO(美国新泽西州萨默维尔市爱惜康女性健康与泌尿外科公司),使用一条缩短至12厘米长的聚丙烯吊带。此外,避免用剪刀和导针穿透闭孔膜,以减少外侧解剖的深度,从而最大程度地确保吊带固定在闭孔肌/腱膜结构内。在一项比较解剖学研究中,确实观察到较短的吊带穿过的肌肉结构比原来的少(内收肌中没有或仅有极少量吊带),同时仍能始终如一地在距闭孔管同样安全的距离处固定在闭孔膜上。在一项单中心随机临床试验中,经过至少3年的随访,发现采用较短吊带并减少解剖的改良TVT-O手术在治疗女性SUI方面与原手术一样安全有效,且术后即刻腹股沟疼痛的严重程度和频率更低。

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