Schröder C H, Urbaczka G
J Gen Virol. 1979 Sep;44(3):827-31. doi: 10.1099/0022-1317-44-3-827.
The sensitivity of interfering herpes simplex virus (HSV) particles to u.v.-irradiation was studied in a virus stock of HSV-1 strain ANG that contained an excess of interfering over infectious particles. Following u.v.-irradiation, samples of this virus stock were assayed for their plaque-forming capacity and their capacity to interfere with the replication of unirradiated standard virus. Depending on the assay conditions, interfering particles appeared to be less, equally, or more sensitive to u.v. light than infectious particles. It is concluded that interference is a gene function of interfering particles rather than being exerted directly by structural constituents of these particles.
在含有过量干扰颗粒而非感染性颗粒的单纯疱疹病毒1型ANG株病毒原液中，研究了干扰性单纯疱疹病毒（HSV）颗粒对紫外线照射的敏感性。紫外线照射后，对该病毒原液的样本进行噬斑形成能力以及干扰未照射标准病毒复制能力的检测。根据检测条件，干扰颗粒对紫外线的敏感性似乎低于、等同于或高于感染性颗粒。得出的结论是，干扰是干扰颗粒的一种基因功能，而非由这些颗粒的结构成分直接发挥作用。
