Schröder C H, Urbaczka G
J Gen Virol. 1978 Dec;41(3):493-501. doi: 10.1099/0022-1317-41-3-493.
The capacity of herpes simplex virus to kill cells and to form both infectious centres and progeny virus was studied in cell culture. Two virus stocks were compared at various m.o.i.: (i) a standard virus stock and (ii) a stock which contained interfering virus particles (I particles). The formation of infectious progeny virus as well as of infectious centres appeared to be reduced by the action of I particles. In the examined virus stock I particles exceeded infectious particles by at least a factor of 5 to 10. More than 50% of cells which could be demonstrated to be hit by I particles survived and formed colonies.
在细胞培养中研究了单纯疱疹病毒杀死细胞以及形成感染中心和子代病毒的能力。在不同的感染复数下比较了两种病毒毒株：（i）一种标准病毒毒株和（ii）一种含有干扰病毒颗粒（I颗粒）的毒株。I颗粒的作用似乎减少了感染性子代病毒以及感染中心的形成。在所检测的病毒毒株中，I颗粒比感染性颗粒至少多5到10倍。超过50%可证明被I颗粒侵袭的细胞存活并形成了集落。
