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线性化BK病毒DNA诱导的转化和T抗原

Transformation and T antigen induction by linearized BK virus DNA.

作者信息

van der Noordaa J, De Jong W, Pauw W, Sol C J, van Strien A

出版信息

J Gen Virol. 1979 Sep;44(3):843-7. doi: 10.1099/0022-1317-44-3-843.

Abstract

Linearized unit length DNA obtained after cleavage of the supercoiled DNA of the human papovavirus BKV by PstI (.031) induced transformation and T antigen less efficiently than DNA cleaved by EcoRI (0.0), BamHI (0.98), KpnI (0.90) or HhaI (0.73). BKV DNA cleaved by XbaI (0.27 and 0.95) did not induce T antigen.

摘要

人乳头多瘤空泡病毒BKV的超螺旋DNA经PstI(0.031)切割后获得的线性单位长度DNA诱导转化和T抗原的效率低于经EcoRI(0.0)、BamHI(0.98)、KpnI(0.90)或HhaI(0.73)切割的DNA。经XbaI(0.27和0.95)切割的BKV DNA未诱导T抗原。

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引用本文的文献

1
Free viral DNA in BK virus-induced hamster tumor cells.
J Virol. 1980 Aug;35(2):331-9. doi: 10.1128/JVI.35.2.331-339.1980.

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