GS病毒与BK病毒基因组的比较分析。
Comparative analysis of GS and BK virus genomes.
作者信息
Pater M M, Pater A, di Mayorca G
出版信息
J Virol. 1979 Oct;32(1):220-5. doi: 10.1128/JVI.32.1.220-225.1979.
Abstract
Analysis of heteroduplexing between the genomes of GS virus, a BK-group virus, and the prototype BK virus revealed one region of nonhomology. Further analysis by cleavage of viral DNA with the restriction endonucleases EcoRI, HindIII, and HaeIII revealed that base changes in the GS virus genome spanned 0.6 to 0.7 map unit from the EcoRI site. Large T and small t antigens of GS virus appear to be similar in size to the BK virus antigens.
摘要
对BK组病毒GS病毒的基因组与原型BK病毒之间的异源双链分析显示出一个非同源区域。通过用限制性内切酶EcoRI、HindIII和HaeIII切割病毒DNA进行的进一步分析表明，GS病毒基因组中的碱基变化从EcoRI位点起跨度为0.6至0.7个图谱单位。GS病毒的大T抗原和小t抗原在大小上似乎与BK病毒抗原相似。
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