从尿路上皮信号传递到体验与膀胱相关的感觉。
From urothelial signalling to experiencing a sensation related to the urinary bladder.
机构信息
Departments of Medicine and Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
出版信息
Acta Physiol (Oxf). 2013 Jan;207(1):34-9. doi: 10.1111/apha.12011. Epub 2012 Oct 30.
Abstract
The mechanisms underlying bladder sensation and the way we experience sensations during normal voiding and in pathology is complex and not well understood. During storage and emptying, mechanical changes occurring in number of cell types within the bladder wall (i.e. the uroepithelium and bladder afferents) can have a major influence on our sensory systems. In this review, we discuss bladder sensation with a focus on coding events in the periphery.
摘要
膀胱感觉的机制以及我们在正常排尿和病理状态下感知感觉的方式非常复杂，目前尚未完全理解。在储存和排空过程中，膀胱壁内多种细胞类型（即尿路上皮和膀胱传入神经）发生的机械变化可能会对我们的感觉系统产生重大影响。在这篇综述中，我们重点讨论了膀胱感觉，特别是对周围编码事件的讨论。
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