表面活性剂在本体水和二棕榈酰磷脂酰胆碱囊泡膜之间的分配：固体凝胶膜与液晶膜

Surfactant partition between bulk water and DPPC vesicle membrane: solid-gel vs. liquid-crystalline membrane.

作者信息

Inoue T, Fukushima K, Shimozawa R

机构信息

Department of Chemistry, Faculty of Science, Fukuoka University, Japan.

出版信息

Chem Phys Lipids. 1990 Jan;52(2):157-61. doi: 10.1016/0009-3084(90)90159-o.

DOI:10.1016/0009-3084(90)90159-o

PMID:2311141

Abstract

The main phase transition temperature, Tm, of dipalmitoylphosphatidylcholine (DPPC) vesicle membrane was measured in the presence of the cationic surfactants tetradecyltrimethylammonium bromide and hexadecyltrimethylammonium bromide. Variation of the perturbing effect of these surfactants on Tm with the lipid concentration was analyzed according to the theory recently proposed by Kaminoh et al. (Y. Kaminoh, C. Tashiro, H. Kamaya and I. Ueda (1988) Biochim. Biophys. Acta 946, 215-220), and the partition coefficients of the surfactant into solid-gel and liquid-crystalline membranes were estimated.

摘要

在阳离子表面活性剂十四烷基三甲基溴化铵和十六烷基三甲基溴化铵存在的情况下，测定了二棕榈酰磷脂酰胆碱（DPPC）囊泡膜的主要相变温度Tm。根据Kaminoh等人最近提出的理论（Y. Kaminoh, C. Tashiro, H. Kamaya和I. Ueda (1988) Biochim. Biophys. Acta 946, 215 - 220），分析了这些表面活性剂对Tm的扰动效应随脂质浓度的变化，并估算了表面活性剂在固体凝胶和液晶膜中的分配系数。