Horowitz-Kraus Tzipi, Breznitz Zvia
1The Edmond J. Safra Brain Research Center for the Study of Learning Disabilities, Faculty of Education, University of Haifa, Israel.
J Child Neurol. 2013 Oct;28(10):1266-76. doi: 10.1177/0883073812460917. Epub 2012 Oct 30.
Error/correct-related negativities, response-locked components of the evoked response potential, and N100, a stimulus-locked component, were used to compare error detection monitoring in skilled readers and in compensated and noncompensated dyslexic adolescent readers during a lexical decision task. Results showed a general increase in N100 amplitudes prior to error commission in all groups; a significant decrease in error/correct-related negativity amplitudes in the noncompensated dyslexics compared with the other 2 groups; and smaller error-related negativity correlated with a higher number of decoding errors, lower working memory scores, and lower speed of processing in the neuropsychological battery. Based on the hypothesis in previous studies that the error detection mechanism is a subcomponent of executive functions, the possibility that poor executive ability underlies poor reading skills in the noncompensated dyslexic readers is discussed. These findings can be used as a platform for executive-based diagnosis and training for individuals with reading disabilities.
错误/纠正相关负波、诱发反应电位的反应锁定成分以及刺激锁定成分N100，被用于比较熟练阅读者、代偿性和非代偿性阅读障碍青少年阅读者在词汇判断任务中的错误检测监测情况。结果显示，所有组在犯错前N100波幅普遍增加；与其他两组相比，非代偿性阅读障碍者的错误/纠正相关负波幅显著降低；且较小的错误相关负波与更高的解码错误数量、更低的工作记忆分数以及神经心理测验中更低的加工速度相关。基于先前研究中错误检测机制是执行功能子成分的假设，讨论了非代偿性阅读障碍阅读者执行能力差是阅读技能差的潜在原因这一可能性。这些发现可作为对阅读障碍个体进行基于执行功能的诊断和训练的平台。
