急诊科胸痛或等效性心绞痛症状患者血清肌钙蛋白I升高与早期预后
Increasing serum troponin I and early prognosis in patients with chest pain or angina equivalent symptoms in the emergency department.
作者信息
Davarani Hh, Afzalimoghadam M, Hosseinnejad H, Hamidian R
机构信息
Dept. of Emergency Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Iran J Public Health. 2012;41(2):63-9. Epub 2012 Feb 29.
BACKGROUND
The purpose of this research was to determine the relation between negative or positive qualitative troponin I test and the short term prognosis of patients presenting to emergency department with chest pain or angina equivalent symptoms.
METHODS
we assessed the qualitative rapid troponin I in patients with chest pain or angina equivalent symptoms after at least 4 hours and then we followed the patients in 72 hours after presentation for adverse events such as death, CCU admission, fatal arrhythmias and heart failure.
RESULTS
After comparing qualitative troponin I test results and adverse events, we concluded that the troponin I was significantly more positive in patients with adverse events (i.e. CCU admission, fatal arrhythmias and heart failure) (P=0.031).
CONCLUSION
A single measurement of rapid qualitative troponin I test can be used as a prognostic factor in patients with chest pain or angina equivalent symptoms and also as a device for risk stratification of moderate and high risk patients.
背景
本研究的目的是确定定性肌钙蛋白I检测结果为阴性或阳性与因胸痛或类心绞痛症状就诊于急诊科的患者短期预后之间的关系。
方法
我们对有胸痛或类心绞痛症状的患者在至少4小时后进行了定性快速肌钙蛋白I检测，然后在患者就诊后的72小时内对其进行随访，观察不良事件，如死亡、入住冠心病监护病房（CCU）、致命性心律失常和心力衰竭。
结果
在比较定性肌钙蛋白I检测结果和不良事件后，我们得出结论，不良事件（即入住CCU、致命性心律失常和心力衰竭）患者的肌钙蛋白I阳性率显著更高（P = 0.031）。
结论
单次快速定性肌钙蛋白I检测可作为有胸痛或类心绞痛症状患者的预后因素，也可作为中高危患者风险分层的手段。
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