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Iran J Public Health. 2012;41(2):63-9. Epub 2012 Feb 29.
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Emergency department and office-based evaluation of patients with chest pain.胸痛患者的急诊科和基于诊室的评估。
Mayo Clin Proc. 2010 Mar;85(3):284-99. doi: 10.4065/mcp.2009.0560.
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Acute myocardial infarction.急性心肌梗死
Lancet. 2008 Aug 16;372(9638):570-84. doi: 10.1016/S0140-6736(08)61237-4.
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Growth-differentiation factor-15 for early risk stratification in patients with acute chest pain.生长分化因子-15用于急性胸痛患者的早期风险分层
Eur Heart J. 2008 Oct;29(19):2327-35. doi: 10.1093/eurheartj/ehn339. Epub 2008 Jul 29.
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Long-term health outcomes associated with detectable troponin I concentrations.与可检测到的肌钙蛋白I浓度相关的长期健康结果。
Clin Chem. 2007 Feb;53(2):220-7. doi: 10.1373/clinchem.2006.076885. Epub 2007 Jan 4.
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Short term prognosis of patients with acute coronary syndromes: the level of cardiac troponin T elevation corresponding to the "old" WHO definition of myocardial infarction.急性冠状动脉综合征患者的短期预后:与世界卫生组织“旧”心肌梗死定义相对应的心肌肌钙蛋白T升高水平
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Acute myocardial infarction.急性心肌梗死
Lancet. 2003 Mar 8;361(9360):847-58. doi: 10.1016/S0140-6736(03)12712-2.
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A prospective survey of the characteristics, treatments and outcomes of patients with acute coronary syndromes in Europe and the Mediterranean basin; the Euro Heart Survey of Acute Coronary Syndromes (Euro Heart Survey ACS).欧洲和地中海地区急性冠脉综合征患者的特征、治疗及预后的前瞻性调查;欧洲急性冠脉综合征心脏调查(欧洲心脏调查急性冠脉综合征)
Eur Heart J. 2002 Aug;23(15):1190-201. doi: 10.1053/euhj.2002.3193.
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Myocardial infarction: redefined or reinvented?心肌梗死:重新定义还是彻底重塑?
Heart. 2002 Jul;88(1):1-3. doi: 10.1136/heart.88.1.1.
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Twenty-two year (1975 to 1997) trends in the incidence, in-hospital and long-term case fatality rates from initial Q-wave and non-Q-wave myocardial infarction: a multi-hospital, community-wide perspective.1975年至1997年期间,22年里初始Q波型和非Q波型心肌梗死的发病率、住院病死率及长期病死率趋势:多医院、全社区视角研究。
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A classification of unstable angina revisited.不稳定型心绞痛的重新分类。
Circulation. 2000 Jul 4;102(1):118-22. doi: 10.1161/01.cir.102.1.118.

急诊科胸痛或等效性心绞痛症状患者血清肌钙蛋白I升高与早期预后

Increasing serum troponin I and early prognosis in patients with chest pain or angina equivalent symptoms in the emergency department.

作者信息

Davarani Hh, Afzalimoghadam M, Hosseinnejad H, Hamidian R

机构信息

Dept. of Emergency Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Public Health. 2012;41(2):63-9. Epub 2012 Feb 29.

PMID:23113136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3481681/
Abstract

BACKGROUND

The purpose of this research was to determine the relation between negative or positive qualitative troponin I test and the short term prognosis of patients presenting to emergency department with chest pain or angina equivalent symptoms.

METHODS

we assessed the qualitative rapid troponin I in patients with chest pain or angina equivalent symptoms after at least 4 hours and then we followed the patients in 72 hours after presentation for adverse events such as death, CCU admission, fatal arrhythmias and heart failure.

RESULTS

After comparing qualitative troponin I test results and adverse events, we concluded that the troponin I was significantly more positive in patients with adverse events (i.e. CCU admission, fatal arrhythmias and heart failure) (P=0.031).

CONCLUSION

A single measurement of rapid qualitative troponin I test can be used as a prognostic factor in patients with chest pain or angina equivalent symptoms and also as a device for risk stratification of moderate and high risk patients.

摘要

背景

本研究的目的是确定定性肌钙蛋白I检测结果为阴性或阳性与因胸痛或类心绞痛症状就诊于急诊科的患者短期预后之间的关系。

方法

我们对有胸痛或类心绞痛症状的患者在至少4小时后进行了定性快速肌钙蛋白I检测,然后在患者就诊后的72小时内对其进行随访,观察不良事件,如死亡、入住冠心病监护病房(CCU)、致命性心律失常和心力衰竭。

结果

在比较定性肌钙蛋白I检测结果和不良事件后,我们得出结论,不良事件(即入住CCU、致命性心律失常和心力衰竭)患者的肌钙蛋白I阳性率显著更高(P = 0.031)。

结论

单次快速定性肌钙蛋白I检测可作为有胸痛或类心绞痛症状患者的预后因素,也可作为中高危患者风险分层的手段。