a Institute of Inflammation and Repair, University of Manchester , Manchester , UK .
Psychol Health Med. 2013;18(5):501-14. doi: 10.1080/13548506.2012.736625. Epub 2012 Nov 2.
Psoriasis remains incurable and many sufferers experience related psychological distress and a lower quality of life comparable with other chronic diseases. A subpopulation of people with psoriasis believes their condition is exacerbated by psychological stress. This review analyses whether stress-reduction interventions can reduce: the physical severity of psoriasis and related psychological distress. A systematic search across EMBASE, MEDLINE, The Cochrane Library SIGLE and PsychInfo, identified 730 trials and 10 were included. Three trials found a significant difference in psoriasis outcomes between groups post-intervention, (p < 0.05). Seven studies included a psychological outcome and three found a significant difference (p < 0.05). Three trials included a quality of life measurement and one of these reported a significant improvement (p < 0.001). Due to low quality evidence it is currently insufficient to judge stress reduction interventions as either effective or ineffective. We make nine recommendations for future research in this multidisciplinary field.
银屑病仍然无法治愈，许多患者经历相关的心理困扰和生活质量下降，与其他慢性疾病相当。一部分银屑病患者认为他们的病情因心理压力而加重。本综述分析了减轻压力干预措施是否可以降低：银屑病的身体严重程度和相关的心理困扰。通过对 EMBASE、MEDLINE、The Cochrane Library SIGLE 和 PsychInfo 进行系统搜索，共确定了 730 项试验，其中有 10 项被纳入。三项试验发现干预后组间在银屑病结局方面存在显著差异（p<0.05）。七项研究纳入了心理结局，其中三项发现了显著差异（p<0.05）。三项试验纳入了生活质量测量，其中一项报告了显著改善（p<0.001）。由于证据质量低，目前还不足以判断减轻压力干预措施是否有效或无效。我们在这个多学科领域提出了九条未来研究的建议。
