Key Laboratory of Food Safety Risk Assessment, Ministry of Health, China National Center for Food Safety Risk Assessment, No. 7 Panjiayuan Nanli, Chaoyang District, Beijing 100021, PR China.
J Agric Food Chem. 2012 Nov 21;60(46):11638-46. doi: 10.1021/jf3038133. Epub 2012 Nov 13.
A total of 969 corn kernels and corn-based products collected from 24 provinces in China between 2008 and 2011 were analyzed for deoxynivalenol, deoxynivalenol 3-glucoside, 3-acetyl-deoxynivalenol, and 15-acetyl-deoxynivalenol by ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Deoxynivalenol was the predominant mycotoxin detected. A total of 29 out of 969 samples (corn kernels: 9/289, mean = 1884 μg/kg; corn-based products: 20/680, mean = 1580 μg/kg) contain deoxynivalenol at the levels exceeding the Chinese regulatory limit of 1000 μg/kg for deoxynivalenol in corn. The average relative concentration ratios (%) for deoxynivalenol 3-glucoside/deoxynivalenol for all four years were 25% ± 5% in corn kernels and 34% ± 4% in corn-based products. The results of this study indicate that it is necessary to include deoxynivalenol 3-glucoside in both risk assessment of deoxynivalenol and its derivatives and development of the tolerance limit for deoxynivalenol in Chinese corn kernels and corn-based products.
2008 年至 2011 年期间，在中国 24 个省共采集了 969 份玉米籽粒和玉米制品样本，采用超高效液相色谱-串联质谱法（UPLC-MS/MS）对其进行脱氧雪腐镰刀菌烯醇、脱氧雪腐镰刀菌烯醇 3-葡萄糖苷、3-乙酰脱氧雪腐镰刀菌烯醇和 15-乙酰脱氧雪腐镰刀菌烯醇的检测。结果表明，脱氧雪腐镰刀菌烯醇是主要的真菌毒素。在所检测的 969 份样本中，有 29 份（玉米籽粒：9/289，平均值为 1884μg/kg；玉米制品：20/680，平均值为 1580μg/kg）的脱氧雪腐镰刀菌烯醇含量超过中国玉米中脱氧雪腐镰刀菌烯醇限量标准（1000μg/kg）。四年间，玉米籽粒中脱氧雪腐镰刀菌烯醇 3-葡萄糖苷/脱氧雪腐镰刀菌烯醇的平均相对浓度比（%）为 25%±5%，玉米制品中的平均相对浓度比（%）为 34%±4%。本研究结果表明，在对脱氧雪腐镰刀菌烯醇及其衍生物进行风险评估和制定中国玉米和玉米制品中脱氧雪腐镰刀菌烯醇限量标准时，有必要将脱氧雪腐镰刀菌烯醇 3-葡萄糖苷纳入考量。
