Jaeger-Denavit O, Alphonse A
INSERM U 215 "Handicap moteur neurologique et croissance", Hopital Raymond Poincaré, Garches, France.
Eur Respir J. 1990 Feb;3(2):197-201.
Good theoretical values for vital capacity (VCt) can be used to calculate a VC/VCt ratio which remains constant for a given individual subject throughout different growth periods. This longitudinal study on 27 boys was performed in order to determine whether a single equation was accurate throughout the growth of boys. The mean values of VC/VCt were also compared for the beginning and end of the prepubertal period in 57 boys and between the beginning and end of puberty in 40 boys. VCt was calculated from five reference equations using data from boys with average age 8-16 yrs, and from two equations using data specific to children and adolescents. The mean VC/VCt ratio was found to fall between the beginning and end of the prepubertal period and to increase very significantly between the beginning and end of the pubertal period when the reference equation used had been calculated using data from populations containing both pubertal and prepubertal subjects. When the equations established from adolescents were used, VC/VCt fell slightly between the beginning and end of the pubertal period. We conclude that data for children and adolescents should be treated separately when establishing reference values for VC.
肺活量（VCt）的良好理论值可用于计算VC/VCt比值，对于给定的个体受试者，该比值在不同的生长阶段保持恒定。进行这项针对27名男孩的纵向研究，目的是确定一个单一方程在男孩整个生长过程中是否准确。还比较了57名男孩青春期前阶段开始和结束时以及40名男孩青春期开始和结束时的VC/VCt平均值。VCt是根据五个参考方程，使用平均年龄为8 - 16岁男孩的数据计算得出的，还有两个方程是使用儿童和青少年的特定数据计算得出的。当使用的参考方程是根据包含青春期和青春期前受试者的人群数据计算得出时，发现青春期前阶段开始和结束时的平均VC/VCt比值下降，而青春期开始和结束时则非常显著地增加。当使用从青少年建立的方程时，VC/VCt在青春期开始和结束时略有下降。我们得出结论，在建立VC的参考值时，儿童和青少年的数据应分开处理。
