Ali Arif, Gosavi Milind, Michael Rajiv, Mathew John, Kurien Mary, Korula Anila
Department of ENT, Speech and Hearing, Christian Medical College and Hospital, Vellore, Tamilnadu, India.
Indian J Otolaryngol Head Neck Surg. 2004 Oct;56(4):314-6. doi: 10.1007/BF02974400.
Chondrosarcoma of the head and neck region are relatively uncommon, arising rarely in the naval septum. The reported cases of nasal septal chondrosarcomas are extensive lesions with involvement of paranasal sinuses, orbit or skull base at the lime of diagnosis. Those limited to the nasal cavity is extremely rare and to date there has been one case report in English language literature. We present a case of chondrosarcoma of the nasal septum with involvement of the nasal cavity alone and no evidence of bony erosion. Initial multiple biopsies showed mature chondromatous areas with no atypia. The patient had wide excision of the tumour. The final biopsy of the excised specimen revealed foci of well-differentiated chondrosarcoma. Wide surgical excision with adequate margins should be considered as the treatment of choice in lesion of nasal septum even if initial biopsies are negative for malignancy. Hence this case report.
头颈部软骨肉瘤相对少见,很少发生于鼻中隔。已报道的鼻中隔软骨肉瘤病例在诊断时多为广泛病变,累及鼻窦、眼眶或颅底。局限于鼻腔的情况极为罕见,迄今为止英文文献中仅有一例病例报告。我们报告一例仅累及鼻腔而无骨质侵蚀证据的鼻中隔软骨肉瘤病例。最初的多次活检显示为成熟的软骨瘤区域,无异型性。患者接受了肿瘤广泛切除术。切除标本的最终活检显示为高分化软骨肉瘤灶。即使最初的活检结果为恶性阴性,对于鼻中隔病变,应考虑采用具有足够切缘的广泛手术切除作为首选治疗方法。因此有了本病例报告。