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鼻中隔巨大软骨肉瘤

A Huge Chondrosarcoma of the Nasal Septum.

作者信息

Aziz Azliana, Mohamed Mohamed A Malik, Khan Mohammad Habibullah

机构信息

Otorhinolaryngology, Head and Neck Surgery (ORL-HNS), Universiti Sains Malaysia School of Medical Sciences, Kota Bharu, MYS.

Otorhinolaryngology, South Infirmary-Victoria University Hospital, Cork, IRL.

出版信息

Cureus. 2022 Jul 31;14(7):e27532. doi: 10.7759/cureus.27532. eCollection 2022 Jul.

DOI:10.7759/cureus.27532
PMID:36060410
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9427330/
Abstract

Chondrosarcoma of the nasal septum is a rare malignancy. Its early diagnosis is difficult because of its non-specific sinonasal complaints. We report a case report of a 72-year-old woman who presented with progressive nasal obstruction and anosmia. Nasal endoscopy showed a nasal mass obstructing both nasal cavities, which was not separable from the nasal septum. Endoscopic biopsy confirmed chondrosarcoma. The tumour was operated on with complete margins by an endoscopic approach. The clinical presentation of the disease, diagnosis and treatment of this case, and a review of the literature are discussed.

摘要

鼻中隔软骨肉瘤是一种罕见的恶性肿瘤。由于其鼻窦症状不具特异性，早期诊断较为困难。我们报告一例72岁女性患者，表现为进行性鼻塞和嗅觉减退。鼻内镜检查显示鼻腔肿物阻塞双侧鼻腔，与鼻中隔相连。内镜活检确诊为软骨肉瘤。通过内镜手术完整切除肿瘤边缘。本文讨论了该疾病的临床表现、本病例的诊断和治疗，并对相关文献进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/74c36bcaf890/cureus-0014-00000027532-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/fac2787de90a/cureus-0014-00000027532-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/7605e5ce0444/cureus-0014-00000027532-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/d2ad0813043a/cureus-0014-00000027532-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/68f6822aaa23/cureus-0014-00000027532-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/336064e02f22/cureus-0014-00000027532-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/e8414d4dd473/cureus-0014-00000027532-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/7ad223565fe9/cureus-0014-00000027532-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/698f1bf744d3/cureus-0014-00000027532-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/74c36bcaf890/cureus-0014-00000027532-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/fac2787de90a/cureus-0014-00000027532-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/7605e5ce0444/cureus-0014-00000027532-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/d2ad0813043a/cureus-0014-00000027532-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/68f6822aaa23/cureus-0014-00000027532-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/336064e02f22/cureus-0014-00000027532-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/e8414d4dd473/cureus-0014-00000027532-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/7ad223565fe9/cureus-0014-00000027532-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/698f1bf744d3/cureus-0014-00000027532-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/279f/9427330/74c36bcaf890/cureus-0014-00000027532-i09.jpg

相似文献

1
A Huge Chondrosarcoma of the Nasal Septum.鼻中隔巨大软骨肉瘤
Cureus. 2022 Jul 31;14(7):e27532. doi: 10.7759/cureus.27532. eCollection 2022 Jul.
2
Chondrosarcoma of the nasal septum.鼻中隔软骨肉瘤
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3
Open resection and reconstruction of a Nasoseptal Chondrosarcoma: case report and literature review.鼻-鼻中隔软骨肉瘤的开放性切除与重建：病例报告及文献复习。
J Otolaryngol Head Neck Surg. 2020 Mar 24;49(1):15. doi: 10.1186/s40463-020-00409-6.
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Endoscopic removal of a nasal septum chondrosarcoma.鼻内镜下切除鼻中隔软骨肉瘤
Rhinology. 2002 Jun;40(2):96-9.
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Chondrosarcoma of the nasal septum: a case report.
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Chondrosarcoma of posterior nasal septum.
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Extensive Chondrosarcoma of the Nasal Septum: Endoscopic Resection and Long-Term Follow-Up.鼻中隔广泛软骨肉瘤：内镜下切除及长期随访
J Craniofac Surg. 2016 Jun;27(4):976-7. doi: 10.1097/SCS.0000000000002634.
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Chondrosarcoma of the nasal septum: A case report.鼻中隔软骨肉瘤：一例报告。
Auris Nasus Larynx. 2009 Oct;36(5):601-5. doi: 10.1016/j.anl.2008.12.006. Epub 2009 Mar 17.
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Actinomycosis of the Nasal Septum: A Rare Entity.鼻中隔放线菌病：一种罕见病症。
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本文引用的文献

1
Chondrosarcoma of the nasal cavity in a patient with Maffucci syndrome: case report and review of the literature.马富西综合征患者鼻腔软骨肉瘤：病例报告及文献复习
World J Surg Oncol. 2014 Dec 17;12:387. doi: 10.1186/1477-7819-12-387.
2
Management of sinonasal chondrosarcoma: a systematic review of 161 patients.鼻窦软骨肉瘤的治疗：161 例患者的系统回顾。
Int Forum Allergy Rhinol. 2013 Aug;3(8):670-7. doi: 10.1002/alr.21162. Epub 2013 Mar 20.
3
Chondrosarcoma of the nasal septum.鼻中隔软骨肉瘤
Indian J Otolaryngol Head Neck Surg. 2004 Oct;56(4):314-6. doi: 10.1007/BF02974400.
4
Chondrosarcoma of the nasal septum: A case report.鼻中隔软骨肉瘤：一例报告。
Auris Nasus Larynx. 2009 Oct;36(5):601-5. doi: 10.1016/j.anl.2008.12.006. Epub 2009 Mar 17.
5
Chondrosarcoma of the nasal septum.
Ear Nose Throat J. 2009 Jan;88(1):744-5.
6
The clinical approach towards chondrosarcoma.软骨肉瘤的临床治疗方法。
Oncologist. 2008 Mar;13(3):320-9. doi: 10.1634/theoncologist.2007-0237.
7
Chondrosarcoma of the nasal septum: a case report.
Kulak Burun Bogaz Ihtis Derg. 2004;12(1-2):39-41.
8
Chondrosarcoma of the head and neck.头颈部软骨肉瘤
Yonsei Med J. 2005 Apr 30;46(2):228-32. doi: 10.3349/ymj.2005.46.2.228.
9
Unusual benign and malignant chondroid tumors of bone. A survey of some mesenchymal cartilage tumors and malignant chondroblastic tumors, including a few multicentric ones, as well as many atypical benign chondroblastomas and chondromyxoid fibromas.骨的罕见良性和恶性软骨样肿瘤。对一些间叶性软骨肿瘤和恶性成软骨细胞瘤的调查，包括少数多中心性肿瘤，以及许多非典型良性成软骨细胞瘤和软骨黏液样纤维瘤。
Cancer. 1959 Nov-Dec;12:1142-57. doi: 10.1002/1097-0142(195911/12)12:6<1142::aid-cncr2820120610>3.0.co;2-d.
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Chondrosarcoma of the nasal septum.鼻中隔软骨肉瘤
Otolaryngol Head Neck Surg. 2001 Jul;125(1):98-100. doi: 10.1067/mhn.2001.116236.