鼻脑型毛霉菌病：一种呈上升趋势的致命疾病。
Rhinocerebral mucormycosis: A deadly disease on the rise.
作者信息
Mane R S, Watve J K, Mohite A A, Patil B C
机构信息
Dept. of ENT, Dr. D.Y. Patil Medical College Hospital, Kadamwadi Kolhapur, India.
出版信息
Indian J Otolaryngol Head Neck Surg. 2007 Jun;59(2):112-5. doi: 10.1007/s12070-007-0034-1. Epub 2007 Sep 14.
According to WHO, there will be epidemic of diabetes world over and India is going to be 'A diabetes capital of the world' by 2025. With the increasing incidence of diabetes, the associated complications are also bound to increase. Rhinocerebral mucormycosis is one of them.Rhinocerebral Mucormycosis is an opportunistic, fulminating fungal infection, caused by Rhizopus species of order of mucorales, frequently seen in diabetic and immunocompromised patients. Mucormycosis has a very high mortality rate.Early diagnosis and treatment with Amphotericin-B is the key to combat this disease successfully. We have seen 13 cases in last 3 years (2002-2005) in our area. This incidence is significant, as this type of cases were rarely seen before 2002, in this geographical area. We present an account of these cases; treatment strategies adopted, review of literature, and highlight 'the role of ENT surgeon in diagnosis and management of this dreadful disease'.
根据世界卫生组织的说法，全球将出现糖尿病流行，到2025年印度将成为“世界糖尿病之都”。随着糖尿病发病率的上升，相关并发症也必然会增加。鼻脑型毛霉菌病就是其中之一。鼻脑型毛霉菌病是一种机会性、暴发性真菌感染，由毛霉目根霉属引起，常见于糖尿病患者和免疫功能低下者。毛霉菌病的死亡率非常高。早期诊断并用两性霉素B治疗是成功对抗这种疾病的关键。在过去三年（2002年至2005年）里，我们地区共接诊了13例。这一发病率值得关注，因为在2002年以前，该地理区域很少见到此类病例。我们介绍这些病例、所采用的治疗策略、文献综述，并着重强调“耳鼻喉科医生在诊断和管理这种可怕疾病中的作用”。
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