Shunyu N B, Thakar A, Gupta V
Department of Otorhinolaryngology and Head & Neck Surgery AIIMS, New Delhi, India.
Indian J Otolaryngol Head Neck Surg. 2008 Sep;60(3):238-41. doi: 10.1007/s12070-008-0085-y. Epub 2008 Oct 22.
Juvenile nasopharyngeal angiofibroma is a benign, locally aggressive, vascular tumour of adolescent males. Extension to intracranial cavity is not uncommon and presents difficulties in management. Here we report a patient who had Radkowsky stage IIIB lesion, with blood supply from internal carotid artery. In view of anticipated problems with surgery, the patient was treated with 30 Gy in 15# external beam radiotherapy. On follow up, tumour was noted to disappear gradually overtime and at 3 years complete disappearance was noted with normal return of vision. Hence we are re-affirming the earlier studies than angiofibroma mass regresses gradually after completion of radiotherapy. Radiotherapy is a useful way of treating angiofibroma with significant intracranial extension.
青少年鼻咽血管纤维瘤是一种发生于青春期男性的良性、局部侵袭性血管肿瘤。肿瘤延伸至颅内腔并不少见，且治疗存在困难。在此，我们报告一名患有Radkowsky IIIB期病变、由颈内动脉供血的患者。鉴于手术可能出现的问题，该患者接受了15次分割、每次剂量30 Gy的外照射放疗。随访发现，肿瘤随时间逐渐消失，3年后完全消失，视力恢复正常。因此，我们再次证实了早期研究的结果，即血管纤维瘤在放疗结束后会逐渐消退。放疗是治疗有明显颅内延伸的血管纤维瘤的一种有效方法。
