Babenko L P, Lazarenko L M, Shynkarenko L M, Mokrozub V V, Pidgorskyi V S, Spivak M Ja
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad Zabolotny St., Kviv, MSP, D03680, Ukraine.
Mikrobiol Z. 2012 Sep-Oct;74(5):116-25.
The effect of intravaginal injection of Lactobacillus casei IMV B-7280, Lactobacillus acidophilus IMV B-7279, Bifidobacterium animalis VKL and Bifidobacterium animalis VKB strains in various compositions on the range of microflora of the urogenital tract on the model of experimental intravaginal staphylococcosis of mice was determined. It was established that under the influence of various compositions of these strains changes in microflora spectrum occurred: the number of representatives of normoflora increased and the number of pathogenic microorganisms, including staphylococci, streptococci, coliform bacteria and fungi, significantly decreased. It was determined that strains of lacto- and bifidobacteria, that were studied, are prospective components of future probiotic drugs efficient in treating staphylococcosis.
测定了在小鼠实验性阴道葡萄球菌病模型中，阴道内注射干酪乳杆菌IMV B-7280、嗜酸乳杆菌IMV B-7279、动物双歧杆菌VKL和动物双歧杆菌VKB菌株的不同组合对泌尿生殖道微生物群落范围的影响。结果表明，在这些菌株的不同组合影响下，微生物群落谱发生了变化：正常菌群代表数量增加，包括葡萄球菌、链球菌、大肠埃希菌和真菌在内的致病微生物数量显著减少。已确定所研究的乳杆菌和双歧杆菌菌株是未来治疗葡萄球菌病有效益生菌药物的潜在成分。
