乳酸杆菌和双歧杆菌与白细胞介素-2的抗葡萄球菌作用
Antistaphylococcal action of lacto- and bifidobacteria and interleukn-2.
作者信息
Mokrozub V V, Lazarenko L M, Babenko L P, Shinkarenko L M, Demchenko O M, Spivak M Ya, Bila V V
机构信息
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad Zabolotny St., Kyiv, D03680, Ukraine.
出版信息
Mikrobiol Z. 2013 Nov-Dec;75(6):17-21.
Antistaphylococcal action of Lactobacillus delbrueckii subsp. bulgaricus IMV B-7281, L. acidophilus LMV B-7279 and Bifidobacterium animalis VKB as well as interleukin-2 (IL-2) has been determined on the model of experimental staphylococcal infection in mice. It has been established that peroral administration of certain probiotic strains of lacto- and bifidobacteria or composition L. acidophilus LMV B-7279--L. delbrueckii subsp. bulgaricus IMV B-7281 with IL-2 to mice favored the reducing of terms of staphylococcus persistence in the kidneys of experimental mice. The studied schemes are promising for treatment of patients with surgical infection.
德氏乳杆菌保加利亚亚种IMV B - 7281、嗜酸乳杆菌LMV B - 7279和动物双歧杆菌VKB以及白细胞介素-2（IL - 2）对小鼠实验性葡萄球菌感染模型的抗葡萄球菌作用已被确定。已证实，给小鼠经口施用某些乳酸菌和双歧杆菌益生菌菌株或嗜酸乳杆菌LMV B - 7279与德氏乳杆菌保加利亚亚种IMV B - 7281的组合物并联合IL - 2，有利于缩短实验小鼠肾脏中葡萄球菌持续存在的时间。所研究的方案对于外科感染患者的治疗具有前景。
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