眼部药物递送：来自纳米技术的线索。 - Suppr

Ocular drug delivery: a clue from nanotechnology.

作者信息

Bucolo Claudio, Drago Filippo, Salomone Salvatore

机构信息

Department of Clinical and Molecular Biomedicine, Section of Pharmacology and Biochemistry, Catania University Catania, Italy.

出版信息

Front Pharmacol. 2012 Oct 25;3:188. doi: 10.3389/fphar.2012.00188. eCollection 2012.

DOI:10.3389/fphar.2012.00188

PMID:23125835

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3486627/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68ca/3486627/7287de39f947/fphar-03-00188-g0001.jpg

相似文献

Ocular drug delivery: a clue from nanotechnology.

Front Pharmacol. 2012 Oct 25;3:188. doi: 10.3389/fphar.2012.00188. eCollection 2012.

Nanotechnology in ocular drug delivery.

Drug Discov Today. 2008 Feb;13(3-4):144-51. doi: 10.1016/j.drudis.2007.10.021.

Nanotechnology in ocular delivery: current and future directions.

Drugs Today (Barc). 2011 Jun;47(6):441-55. doi: 10.1358/dot.2011.47.6.1549023.

Microspheres and Nanotechnology for Drug Delivery.

Dev Ophthalmol. 2016;55:93-103. doi: 10.1159/000434693. Epub 2015 Oct 26.

Novel strategies for anterior segment ocular drug delivery.

J Ocul Pharmacol Ther. 2013 Mar;29(2):106-23. doi: 10.1089/jop.2012.0200. Epub 2012 Dec 5.

The role of nanotechnology in control of human diseases: perspectives in ocular surface diseases.

Crit Rev Biotechnol. 2016 Oct;36(5):777-87. doi: 10.3109/07388551.2015.1036002. Epub 2015 Jul 20.

Glaucoma: Management and Future Perspectives for Nanotechnology-Based Treatment Modalities.

Eur J Pharm Sci. 2021 Mar 1;158:105648. doi: 10.1016/j.ejps.2020.105648. Epub 2020 Nov 21.

Current nanotechnological strategies for treating glaucoma.

Crit Rev Ther Drug Carrier Syst. 2014;31(5):365-405. doi: 10.1615/critrevtherdrugcarriersyst.2014010123.

Nanotechnology-Ocular Devices for Glaucoma Treatment: A Literature Review.

Curr Eye Res. 2019 Feb;44(2):111-117. doi: 10.1080/02713683.2018.1536218. Epub 2018 Oct 22.

Nanocrystal for ocular drug delivery: hope or hype.

Drug Deliv Transl Res. 2016 Aug;6(4):399-413. doi: 10.1007/s13346-016-0292-0.

引用本文的文献

Chitosan-TPP Nanogels for Ocular Delivery of Folic Acid: Release Profile, Corneal Permeation, and Mucoadhesion Assessment.

Pharmaceutics. 2025 Mar 27;17(4):424. doi: 10.3390/pharmaceutics17040424.

Localization of fluorescent gold nanoparticles throughout the eye after topical administration.

Front Med (Lausanne). 2025 Mar 19;12:1557611. doi: 10.3389/fmed.2025.1557611. eCollection 2025.

Nanotherapy for Neural Retinal Regeneration.

Adv Sci (Weinh). 2025 Jun;12(24):e2409854. doi: 10.1002/advs.202409854. Epub 2025 Jan 14.

Ocular mucoadhesive and biodegradable spanlastics loaded cationic spongy insert for enhancing and sustaining the anti-inflammatory effect of prednisolone Na phosphate; Preparation, I-optimal optimization, and In-vivo evaluation.

Int J Pharm X. 2024 Oct 16;8:100293. doi: 10.1016/j.ijpx.2024.100293. eCollection 2024 Dec.

Perspective use of bio-adhesive liquid crystals as ophthalmic drug delivery systems.

Sci Rep. 2023 Sep 27;13(1):16188. doi: 10.1038/s41598-023-42185-z.

Drug-Loaded Polymeric Particulated Systems for Ophthalmic Drugs Release.

Molecules. 2022 Jul 14;27(14):4512. doi: 10.3390/molecules27144512.

Mucoadhesive PLGA Nanospheres and Nanocapsules for Lactoferrin Controlled Ocular Delivery.

Pharmaceutics. 2022 Apr 6;14(4):799. doi: 10.3390/pharmaceutics14040799.

Design of Nanotechnological Carriers for Ocular Delivery of Mangiferin: Preformulation Study.

Molecules. 2022 Feb 16;27(4):1328. doi: 10.3390/molecules27041328.

Do Extracellular RNAs Provide Insight into Uveal Melanoma Biology?

Cancers (Basel). 2021 Nov 25;13(23):5919. doi: 10.3390/cancers13235919.

Nanoemulsions as Ophthalmic Drug Delivery Systems.

Turk J Pharm Sci. 2021 Oct 28;18(5):652-664. doi: 10.4274/tjps.galenos.2020.59319.

本文引用的文献

Polymeric nanoparticles augment the ocular hypotensive effect of melatonin in rabbits.

Int J Pharm. 2013 Jan 20;440(2):135-40. doi: 10.1016/j.ijpharm.2012.10.014. Epub 2012 Oct 16.

Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats.

Biochem Pharmacol. 2012 Jul 1;84(1):88-92. doi: 10.1016/j.bcp.2012.03.019. Epub 2012 Mar 30.

Dopamine-₃ receptor modulates intraocular pressure: implications for glaucoma.

Biochem Pharmacol. 2012 Mar 1;83(5):680-6. doi: 10.1016/j.bcp.2011.11.031. Epub 2011 Dec 8.

PLGA nanospheres for the ocular delivery of flurbiprofen: drug release and interactions.

J Pharm Sci. 2008 Dec;97(12):5306-17. doi: 10.1002/jps.21383.

Diclofenac sodium delivery to the eye: in vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct.

Int J Pharm. 2008 May 1;355(1-2):307-13. doi: 10.1016/j.ijpharm.2007.12.007. Epub 2007 Dec 17.

Nanoparticles sustain expression of Flt intraceptors in the cornea and inhibit injury-induced corneal angiogenesis.

Invest Ophthalmol Vis Sci. 2007 May;48(5):2030-6. doi: 10.1167/iovs.06-0853.

Ocular drug delivery by liposome-chitosan nanoparticle complexes (LCS-NP).

Biomaterials. 2007 Mar;28(8):1553-64. doi: 10.1016/j.biomaterials.2006.11.028. Epub 2006 Dec 13.

Ophthalmic delivery systems based on drug-polymer-polymer ionic ternary interaction: in vitro and in vivo characterization.

Eur J Pharm Biopharm. 2006 Jan;62(1):59-69. doi: 10.1016/j.ejpb.2005.07.002. Epub 2005 Sep 12.

Albumin nanoparticles for the intravitreal delivery of anticytomegaloviral drugs.

Mini Rev Med Chem. 2005 Mar;5(3):293-305. doi: 10.2174/1389557053175335.

Eudragit RL100 nanoparticle system for the ophthalmic delivery of cloricromene.

J Pharm Pharmacol. 2004 Jul;56(7):841-6. doi: 10.1211/0022357023835.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

相似文献

Ocular drug delivery: a clue from nanotechnology.

Front Pharmacol. 2012 Oct 25;3:188. doi: 10.3389/fphar.2012.00188. eCollection 2012.

Nanotechnology in ocular drug delivery.

Drug Discov Today. 2008 Feb;13(3-4):144-51. doi: 10.1016/j.drudis.2007.10.021.

Nanotechnology in ocular delivery: current and future directions.

Drugs Today (Barc). 2011 Jun;47(6):441-55. doi: 10.1358/dot.2011.47.6.1549023.

Microspheres and Nanotechnology for Drug Delivery.

Dev Ophthalmol. 2016;55:93-103. doi: 10.1159/000434693. Epub 2015 Oct 26.

Novel strategies for anterior segment ocular drug delivery.

J Ocul Pharmacol Ther. 2013 Mar;29(2):106-23. doi: 10.1089/jop.2012.0200. Epub 2012 Dec 5.

The role of nanotechnology in control of human diseases: perspectives in ocular surface diseases.

Crit Rev Biotechnol. 2016 Oct;36(5):777-87. doi: 10.3109/07388551.2015.1036002. Epub 2015 Jul 20.

Glaucoma: Management and Future Perspectives for Nanotechnology-Based Treatment Modalities.

Eur J Pharm Sci. 2021 Mar 1;158:105648. doi: 10.1016/j.ejps.2020.105648. Epub 2020 Nov 21.

Current nanotechnological strategies for treating glaucoma.

Crit Rev Ther Drug Carrier Syst. 2014;31(5):365-405. doi: 10.1615/critrevtherdrugcarriersyst.2014010123.

Nanotechnology-Ocular Devices for Glaucoma Treatment: A Literature Review.

Curr Eye Res. 2019 Feb;44(2):111-117. doi: 10.1080/02713683.2018.1536218. Epub 2018 Oct 22.

Nanocrystal for ocular drug delivery: hope or hype.

Drug Deliv Transl Res. 2016 Aug;6(4):399-413. doi: 10.1007/s13346-016-0292-0.

引用本文的文献

Chitosan-TPP Nanogels for Ocular Delivery of Folic Acid: Release Profile, Corneal Permeation, and Mucoadhesion Assessment.

Pharmaceutics. 2025 Mar 27;17(4):424. doi: 10.3390/pharmaceutics17040424.

Localization of fluorescent gold nanoparticles throughout the eye after topical administration.

Front Med (Lausanne). 2025 Mar 19;12:1557611. doi: 10.3389/fmed.2025.1557611. eCollection 2025.

Nanotherapy for Neural Retinal Regeneration.

Adv Sci (Weinh). 2025 Jun;12(24):e2409854. doi: 10.1002/advs.202409854. Epub 2025 Jan 14.

Int J Pharm X. 2024 Oct 16;8:100293. doi: 10.1016/j.ijpx.2024.100293. eCollection 2024 Dec.

Perspective use of bio-adhesive liquid crystals as ophthalmic drug delivery systems.

Sci Rep. 2023 Sep 27;13(1):16188. doi: 10.1038/s41598-023-42185-z.

Drug-Loaded Polymeric Particulated Systems for Ophthalmic Drugs Release.

Molecules. 2022 Jul 14;27(14):4512. doi: 10.3390/molecules27144512.

Mucoadhesive PLGA Nanospheres and Nanocapsules for Lactoferrin Controlled Ocular Delivery.

Pharmaceutics. 2022 Apr 6;14(4):799. doi: 10.3390/pharmaceutics14040799.

Design of Nanotechnological Carriers for Ocular Delivery of Mangiferin: Preformulation Study.

Molecules. 2022 Feb 16;27(4):1328. doi: 10.3390/molecules27041328.

Do Extracellular RNAs Provide Insight into Uveal Melanoma Biology?

Cancers (Basel). 2021 Nov 25;13(23):5919. doi: 10.3390/cancers13235919.

Nanoemulsions as Ophthalmic Drug Delivery Systems.

Turk J Pharm Sci. 2021 Oct 28;18(5):652-664. doi: 10.4274/tjps.galenos.2020.59319.

本文引用的文献

Polymeric nanoparticles augment the ocular hypotensive effect of melatonin in rabbits.

Int J Pharm. 2013 Jan 20;440(2):135-40. doi: 10.1016/j.ijpharm.2012.10.014. Epub 2012 Oct 16.

Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats.

Biochem Pharmacol. 2012 Jul 1;84(1):88-92. doi: 10.1016/j.bcp.2012.03.019. Epub 2012 Mar 30.

Dopamine-₃ receptor modulates intraocular pressure: implications for glaucoma.

Biochem Pharmacol. 2012 Mar 1;83(5):680-6. doi: 10.1016/j.bcp.2011.11.031. Epub 2011 Dec 8.

PLGA nanospheres for the ocular delivery of flurbiprofen: drug release and interactions.

J Pharm Sci. 2008 Dec;97(12):5306-17. doi: 10.1002/jps.21383.

Diclofenac sodium delivery to the eye: in vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct.

Int J Pharm. 2008 May 1;355(1-2):307-13. doi: 10.1016/j.ijpharm.2007.12.007. Epub 2007 Dec 17.

Nanoparticles sustain expression of Flt intraceptors in the cornea and inhibit injury-induced corneal angiogenesis.

Invest Ophthalmol Vis Sci. 2007 May;48(5):2030-6. doi: 10.1167/iovs.06-0853.

Ocular drug delivery by liposome-chitosan nanoparticle complexes (LCS-NP).

Biomaterials. 2007 Mar;28(8):1553-64. doi: 10.1016/j.biomaterials.2006.11.028. Epub 2006 Dec 13.

Ophthalmic delivery systems based on drug-polymer-polymer ionic ternary interaction: in vitro and in vivo characterization.

Eur J Pharm Biopharm. 2006 Jan;62(1):59-69. doi: 10.1016/j.ejpb.2005.07.002. Epub 2005 Sep 12.

Albumin nanoparticles for the intravitreal delivery of anticytomegaloviral drugs.

Mini Rev Med Chem. 2005 Mar;5(3):293-305. doi: 10.2174/1389557053175335.

Eudragit RL100 nanoparticle system for the ophthalmic delivery of cloricromene.

J Pharm Pharmacol. 2004 Jul;56(7):841-6. doi: 10.1211/0022357023835.

Ocular drug delivery: a clue from nanotechnology.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献